Effects of Dietary Lipid Peroxides Contents on In Vivo Lipid Peroxidation, .ALPHA.-Tocopherol Contents, and Superoxide Dismutase and Glutathione Peroxidase Activities in the Liver of Yellowtail.

Sakai, Tadashi; Murata, Hisashi; Yamauchi, Kiyoshi; Sekiya, Tomohiro; Ukawa, Masaharu

doi:10.2331/suisan.58.1483

Cited by 41 publications

(31 citation statements)

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“…Other components are the antioxidant enzymes including free radical scavenging enzymes such as catalase, superoxide dismutase (SOD) and glutathione peroxidase (GPX) and associated enzymes such as glutathione-S-transferase (GST) and glutathione reductase (GR). However, information in relation to in vivo lipid peroxidation and antioxidant defences either in wild or cultured fish species is quite limited Sekiya et al, 1991;Sakai et al, 1992;Murata et al, 1996). In addition, most of the studies have been done in salmonids and freshwater fish (Bell et al, 1984(Bell et al, , 1987Cowey et al, 1985;Radi et al, 1987;Roy et al, 1995) with few studies in marine fish (Stéphan et al, 1995;Murata et al, 1996).…”

Section: Introductionmentioning

confidence: 99%

Relationships between antioxidants, antioxidant enzyme activities and lipid peroxidation products during early development in Dentex dentex eggs and larvae

et al. 1999

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The overall aim is the characterization of the antioxidant systems in marine fish during early development in order to enhance growth and quality of early life stages by avoiding oxidation problems that may cause pathologies and disease. The present study determined the activities of the antioxidant system enzymes and levels of vitamin E, lipid peroxidation products and fatty acids during early development without exogenous feeding in the marine fish, Dentex dentex. Samples of fertilized eggs just prior to hatch, newly hatched larvae and unfed larvae up to day 9 after hatch were analysed on a daily basis.The larvae did not grow during the experiment and by day 9 the surviving larvae weighed only a third of the newly hatched larvae. Lipid was a major energy source during this period of starvation as evidenced by greatly decreased amounts of total lipid due to a preferential utilisation of neutral lipids. All groups of fatty acids (saturated, monounsaturated and polyunsaturated) were consumed throughout the starvation period. Vitamin E levels were relatively constant until significantly declining by days 8 and 9. Similarly, levels of lipid-soluble fluorescent products (LSFP) were relatively constant until day 6 and then significantly decreased from days 7 to 9. In contrast, the level of malondialdehyde (MDA) was very high in eggs but was 3-fold lower in newly hatched larvae and then decreased over the whole time-course and was also significantly lower on days 8 and 9.The activities of enzymes of the antioxidation system were expressed in both eggs and early larvae and varied during the developmental period with levels of catalase and glutathione peroxidase (GPX) being initially low in eggs whereas glutathione-Stransferase (GST) and superoxide dismutase (SOD) were higher in eggs than in larvae.Overall, the activities of catalase and GPX increased, whereas GST and total SOD activities decreased, during the early stages of development during a period where there was no exogenous dietary input into the larvae. Glutathione reductase activity was very low and showed an increasing trend initially until days 2-3 before declining and varying over the remaining period.In conclusion, we determined the prooxidant (polyunsaturated fatty acid) status, antioxidant status (vitamin E), peroxidation status (MDA and LSFP) and the activities of the antioxidant enzyme systems in a single integrated study in unfed marine fish larvae during early development.

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Section: Introductionmentioning

confidence: 99%

Relationships between antioxidants, antioxidant enzyme activities and lipid peroxidation products during early development in Dentex dentex eggs and larvae

et al. 1999

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“…It was reported that oxidative stress caused some undesirable effects in marine animals [14][15][16] . TBARS comprise one of the useful indicators to estimate the oxidative stress [14][15][16] .…”

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confidence: 99%

“…TBARS comprise one of the useful indicators to estimate the oxidative stress [14][15][16] . TBARS values in the liver of FA-and OZ-administrated groups (diet 2-8 groups) were lower than that of the control group (diet 1 group), as shown in .…”

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confidence: 99%

Effects of Dietary Supplementation of Ferulic Acid and .GAMMA.-Oryzanol on Integument Color and Suppression of Oxidative Stress in Cultured Red Sea Bream, Pagrus major

et al. 2008

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The effects of ferulic acid (FA) and g-oryzanol (OZ) supplementation on cultured red sea bream were examined. Commercial brown fish meal diets supplemented with FA (0.01-0.5%) or OZ (0.05-0.5%) were given to zero-year, cultured red sea bream for 98 days. After the experiment, the brightness of the integument color ("L" value) of FA-and OZ-administrated fish was higher than that of control fish. Furthermore, 2-Thiobarbituric acid reactive substances (TBARS) in the liver of FA-and OZadministrated fish was lower than in control fish. These results indicate that FA and OZ suppressed not only dark-color pigmentation but also oxidative stress in cultured red sea bream.

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“…These enzyme activities in fish are known to be induced in tissues suffering from oxidative stress (Sakai et al, 1992;Mourente et al, 2002;Pascual et al, 2003). In humans, the high supplementation of vitamin E has been shown to induce a prooxidant activity.…”

Section: Discussionmentioning

confidence: 99%

Effect of α-tocopherol on antioxidant enzyme activities and lipid peroxidation in rainbow trout (Oncorhynchus mykiss)

Gülçın

Beydemır²,

Hisar³

2005

Acta Veterinaria Hungarica

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In this study, the effect of α-tocopherol on the antioxidant capacity of rainbow trout (Oncorhynchus mykiss) was determined. For this purpose, activities of antioxidant enzymes such as catalase (CAT), peroxidase (POD) and glutathione reductase (GSSG-Rx) were investigated. Enzyme activities were measured at 0 (control), 1, 3 and 5 h after α-tocopherol injection. In addition, the levels of malondialdehyde (MDA) as a lipid peroxidation marker were determined in the erythrocytes. The results showed that α-tocopherol significantly activated the CAT, POD and GSSG-Rx enzymes as compared with the enzyme activities found in the controls (p < 0.05). However, MDA levels were significantly decreased by α-tocopherol treatment (p < 0.05). The results suggest that α-tocopherol may have a pro-oxidant tendency at a high dose and cause mild oxidative stress which could modulate signal transduction cascades, redirect gene expression, and influence many cellular responses such as proliferation, differentiation, and reproduction. For this reason, α-tocopherol should be used carefully in all applications in relation to fish.

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Effects of Dietary Lipid Peroxides Contents on In Vivo Lipid Peroxidation, .ALPHA.-Tocopherol Contents, and Superoxide Dismutase and Glutathione Peroxidase Activities in the Liver of Yellowtail.

Cited by 41 publications

References 0 publications

Relationships between antioxidants, antioxidant enzyme activities and lipid peroxidation products during early development in Dentex dentex eggs and larvae

Relationships between antioxidants, antioxidant enzyme activities and lipid peroxidation products during early development in Dentex dentex eggs and larvae

Effects of Dietary Supplementation of Ferulic Acid and .GAMMA.-Oryzanol on Integument Color and Suppression of Oxidative Stress in Cultured Red Sea Bream, Pagrus major

Effect of α-tocopherol on antioxidant enzyme activities and lipid peroxidation in rainbow trout (Oncorhynchus mykiss)

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