Probiotics and prebiotics in prevention and treatment of diseases in infants and children

Vandenplas, Yvan; Veereman-Wauters, G; Greef, Elisabeth De; Peeters, Stefaan; Casteels, Anne; Mahler, Tania; Devreker, Thierry; Hauser, Bruno

doi:10.2223/jped.2103

Cited by 50 publications

(35 citation statements)

References 108 publications

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“…Although we can argue that these observations could also be the consequence of more aggressive diagnostic approach with repeated endoscopies and imaging procedures in patients with more severe disease during the follow-up period, this could not explain the progression of the disease behavior. It has been postulated that diet is probably the most important factor influencing the composition and function of the intestinal microbiota (46)(47)(48). Similarly, in a large population-based study, Vernier-Massouille et al (39) observed a 2-fold rise in the prevalence of complicated CD behavior during the follow-up.…”

Section: Discussionmentioning

confidence: 97%

Incidence and Phenotypic Characteristics of Pediatric IBD in Northeastern Slovenia, 2002–2010

Urlep

Trop²,

Blagus³

et al. 2014

J. pediatr. gastroenterol. nutr.

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Section: Discussionmentioning

confidence: 97%

Incidence and Phenotypic Characteristics of Pediatric IBD in Northeastern Slovenia, 2002–2010

Urlep

Trop²,

Blagus³

et al. 2014

J. pediatr. gastroenterol. nutr.

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“…Although the role of probiotics is well studied in adults, there were few data on its effectiveness in childhood constipation with contradictory results [1, 3, 9, 10]. Therefore, we conducted this study to evaluate the role of probiotics on our constipated patients.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Probiotics on Childhood Constipation: A Randomized Controlled Double Blind Clinical Trial

Sadeghzadeh

Rabieefar

Khoshnevisasl

et al. 2014

International Journal of Pediatrics

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Background. Inconsistent data exist about the role of probiotics in the treatment of constipated children. The aim of this study was to investigate the effectiveness of probiotics in childhood constipation. Materials and Methods. In this placebo controlled trial, fifty-six children aged 4–12 years with constipation received randomly lactulose plus Protexin or lactulose plus placebo daily for four weeks. Stool frequency and consistency, abdominal pain, fecal incontinence, and weight gain were studied at the beginning, after the first week, and at the end of the 4th week in both groups. Results. Forty-eight patients completed the study. At the end of the fourth week, the frequency and consistency of defecation improved significantly (P = 0.042 and P = 0.049, resp.). At the end of the first week, fecal incontinence and abdominal pain improved significantly in intervention group (P = 0.030 and P = 0.017, resp.) but, at the end of the fourth week, this difference was not significant (P = 0.125 and P = 0.161, resp.). A significant weight gain was observed at the end of the 1st week in the treatment group. Conclusion. This study showed that probiotics had a positive role in increasing the frequency and improving the consistency at the end of 4th week.

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“…A microbiota humano estabelece no início da vida (no parto) sofrendo alterações desde o nascimento (idade gestacional, tipo de parto -parto vaginal ou parto cesariano) e ao longo da vida, influenciado por fatores como idade, alimentação, localização geográfica, o consumo de suplementos e fatores ambientais 16,29,30 . Além das doenças inflamatórias e autoimunes, existem outras doenças crônicas que podem ser afetadas pela comunidade microbiana do intestino.…”

Section: Fatores Determinantes Da Microbiotaunclassified

A importância da microbiota no organismo humano e sua relação com a obesidade

Ramirez¹

2018

Int J Nutrol

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Não há conflito de interesseA importância da microbiota no organismo humano e sua relação com a obesidade 1 Ana Valeria Garcia Ramirez RESUMOEste trabalho é uma revisão bibliográfica com o objetivo de descrever a Importância da microbiota no organismo humano e sua relação com a obesidade. Foram realizadas compilações bibliográficas de artigos científicos originais e de revisão em revistas indexadas, Arquivos Brasileiros de Cardiologia, Scielo PubMed/Medline, SeCS. O trabalho descreveu que a microbiota é uma população de organismos microscópios que habitam o corpo humano. A microbiota intestinal influencia nas doenças gastrointestinais, e em uma variedade de condições imunológicas, como o diabetes mellitus tipo1, doenças cardiovasculares, doenças desmielinizantes autoimunes, alergia, asma, e na obesidade. Há uma associação entre a microbiota intestinal e o peso corporal, havendo uma modificação na composição das bactérias intestinais em obesos diferente das pessoas com IMC normal. O aumento do número de microrganismo promotores da saúde no trato gastrointestinal pode ser feito pela alimentação com prebióticos e probióticos, os quais modificam a composição da microbiota, formando uma barreira contra as bactérias ruins do ecossistema. O trabalho mostrou que com a integridade intestinal é possível evitar o surgimento de doenças impedindo a entrada de microrganismos patógenos e antígenos.Palavras Chaves: microbiota intestinal, obesidade, sobrepeso, metabolismo energético, imunidade. ABSTRACTThis paper is a bibliographic review aiming to describe the importance of microbiota in the human organism and its relationship with obesity. Original scientific articles and reviews from indexed journals such as Brazilian Cardiology articles, Scielo PubMed/Medline, SeCs were compiled. The present work described that microbiota is a population of microscopic organisms that live into the human body. Intestinal microbiota influences gastrointestinal diseases and a great variety of immunological conditions such as, diabetes mellitus type I, cardiovascular diseases, autoimmune demyelinating diseases, allergy, asthma and obesity. There is a close association between intestinal microbiota and body weight due to a modification in bacterial composition of obese people which is different from those with normal BMI. The increase in the number of health promoting microorganisms in the gastrointestinal tract may be achieved by eating prebiotic and probiotic food. They change microbiota composition by creating a barrier against bad bacteria from the ecosystem. Such paper has demonstrated that when preserving intestinal integrity, it is possible to avoid the occurrence of diseases by preventing the entrance of pathogenic and antigenic microorganisms.

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Probiotics and prebiotics in prevention and treatment of diseases in infants and children

Abstract: Duration of administration, microbial dosage, and species used need further validation for both pro- and prebiotics. Unjustified health claims are a major threat for the pro- and prebiotic concept.

Cited by 50 publications

References 108 publications

Incidence and Phenotypic Characteristics of Pediatric IBD in Northeastern Slovenia, 2002–2010

Incidence and Phenotypic Characteristics of Pediatric IBD in Northeastern Slovenia, 2002–2010

The Effect of Probiotics on Childhood Constipation: A Randomized Controlled Double Blind Clinical Trial

A importância da microbiota no organismo humano e sua relação com a obesidade

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