Efficient Encapsulation and Controlled Release of N,N-Diethyl-3-methylbenzamide (DEET) from Oil-in-Water Emulsions Stabilized by Cationic Nanocellulose and Silica Nanoparticles
Luis Gutierrez-Beleño,
Vincenzo Calabrese,
Janet Scott
et al.
Abstract:Oil-in-water emulsions containing N,N-diethyl-3-methylbenzamide (DEET) were developed aiming to extend the sustained release of the active compound, by using two oppositely charged nanomaterials, namely silica nanoparticles (SiNP) and cationic cellulose nanofibrils (CCNF), as stabilizers, and a mixture of food-grade nonionic surfactants to avoid precipitation by electrostatic aggregation. The formulations were stable for more than four months at room temperature, and strongly resistant to destabilization upon … Show more
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