Synthesis, Characterization and Antimicrobial Activities of Pentacyclic Oxadiazadiborinanes

Boron-containing capsaicinoids

“…The desboro-aryl amine substrates were subjected to EDCIassisted amidation using terminally unsaturated aliphatic acids to provide intermediates (27)(28)(29)(30) towards the nal tertiary amide capsaicinoids (31)(32)(33)(34). These intermediates were subjected to metal-catalyzed hydroboration, employing [IrCl(cod)(dppm)] 45 and pinacolborane (HBpin, pin ¼ 1,2-O 2 C 2 Me 4 ) at room temperature.…”

“…Yield: 0.210 g (61%). (br s, 2H), 1.38-1.30 (m, 2H), 1.21-1.16 (m, 20H), 0.73 (t, 2H, J ¼ 7.8 Hz) ppm; 13 (33). General procedure 7 was followed using [Ir(COD)Cl] 2 (0.008 g, 0.01 mmol) and dppm (0.008 g, 0.02 mmol) in THF (2 mL), 29 (0.100 g, 0.229 mmol) in THF (1 mL), and HBPin (0.080 mL, 0.550 mmol) in THF (1 mL) to provide the product as a yellow oil.…”