Microwave Assisted Synthesis of Thiocarbamoylpyrazoles and Application as an Alternative Latent Fingermark Developers

Abstract

Fingerprints are unique to each individual, contributing to human identification in forensic cases. The powder technique being widely used is considered one of the most important in latent fingermarks analysis. In this sense, the present work aimed to synthesize 1-thiocarbamoyl-4,5dihydro-1H-pyrazoles and apply them as powder agents to develop latent fingermarks. The compounds were prepared from an effective and green synthesis via the condensation of chalcones with thiosemicarbazide in ethanol under microwave irradiation. Pyrazoles were tested and compared with a standard white powder (Sirchie ®) on glass surfaces using sebaceous and natural fingermarks so that molecule 2c has been shown to be more promising providing image clarity. The derivatives of pyrazoles were promising as an alternative latent fingermark, presenting high quality images for fingermarks, proving to be a great tool for forensic sciences.

Transition Metal-Free De Novo Synthesis of Sulfonated Pyrazoles from Sulfonyl Hydrazides, 1,3-Diketones, and Sodium Sulfinates at Room Temperature

“…antimicrobial, anticancer, antiinflammatory, antiproliferation, agricultural insecticide, and antioxidation activity . Besides, pyrazoles also play important roles in coordinating chemistry, organometallic chemistry, and latent fingermarks analysis . In addition, substituents on the pyrazole skeleton might also play important roles in the activities.…”

Interpol review of fingermarks and other body impressions (2019 – 2022)

“…Preliminary/Pilot studies – Several compounds were presented as new dusting powders: AIE-active composites or molecules [ [277] , [278] , [279] , [280] , [281] ], algal biomass [ 282 ], anti-perovskite phosphors [ 283 ], azo-dyes [ 284 ], β-cyclodextrin-berberine complexes [ 285 ], benzazole derivatives [ 286 ], bisamide analogues [ 287 ], cadmium-doped silica microspheres [ 288 ], chitosan-tripolyphosphate-lysine conjugates [ 289 ], coumarin–pyridone conjugates [ 290 ], crushed eggshells and clamshells [ 291 ], crushed gambir [ 292 ], curcumin analogues [ 293 ], doped montmorillonite [ 278 , 294 , 295 ], doped starch microspheres [ [296] , [297] , [298] ], europium-dextrose composites [ 299 ], iron oxide/zinc sulphide hybrid [ 300 ], metal-organic frameworks [ 301 ], organic NIR emitters [ 302 , 303 ], perylenetetracarboxylate compounds [ 304 ], phenylthiazoles [ 305 ], phosphor-cellulose hybrids [ 306 ], pyrazoles [ 307 ], pyrene-tagged imidazolium salts [ 308 ], pyridine and pyrimidine derivatives [ 309 , 310 ], rare-earth-doped phosphors [ [311] , [312] , [313] , [314] , [315] , [316] , [317] , [318] , [319] ], reduced graphene oxides [ 320 ], resveratrol powder [ 321 ], rhodamine B-doped diatomaceous earth [ 322 ], Schiff base complexes [ [323] , [324] , [325] ], talcum powder […”