Abstract:Content uniformity (CU) is a parameter used to ensure the uniformity of the amount of active substances in pharmaceutical preparations. It is often evaluated in the quality control of pharmaceutical dosage forms, and a novel method was proposed for CU determination using thermal infrared enthalpimetry (TIE). Captopril tablets were dissolved in 24-well microplates and the heat released from the reaction of captopril and I 2 was monitored with an infrared camera. Some experimental parameters were adjusted, as ca… Show more
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