JBCS 30th Anniversary

In vitro Antiplasmodial Activities of Alkaloids Isolated from Roots of Worsleya procera (Lem.) Traub (Amaryllidaceae)

“…46 Furthermore, a noteworthy feature is the low abundance of the molecular ion peak in all alkaloids with a double bound Δ. 3,4 In this attempt, some alkaloids were detected belonging to the homolycorine-type skeleton, even though they were not identified using only GC-MS techniques. Besides, an ungwedine derivative was detected by GC-MS, but just as traces.…”

“…3 Brazilian biodiversity has an enormous potential for the discovery of new natural products endowed with innovative molecular scaffolds and activity against various diseases. [4][5][6][7] In this sense, plants of the Amaryllidaceae family are promising sources of bioactive molecules. [8][9][10][11][12][13][14][15][16][17][18][19][20] Comprising more than 1600 species worldwide, the Amaryllidaceae family is distinguished by the production of isoquinolinic alkaloids, a privileged scaffold responsible for most of the biological activities observed in these plants.…”