ANTIHYPERTENSIVE AND ANTIDIABETIC PEPTIDES DERIVED FROM IN SILICO SIMULATED GASTROINTESTINAL DIGESTION OF QUINOA (Chenopodium quinoa) GLOBULINS AND MOLECULAR DOCKING STUDY
Rosana Chirinos,
Jamerccy Rodriguez-Diaz,
Sebastian Anticona
et al.
Abstract:This study evaluated the impact of in silico simulated gastrointestinal digestion (GID) of four quinoa globulins on the potential to release ACE and DPP-IV inhibitor peptides (antihypertensive and antidiabetic properties, respectively), as well as performed a molecular docking study to evaluate the interactions produced in the peptide-enzyme complexes. In silico GID performed on quinoa globulins resulted in the formation of amino acids as well as peptides with two to five residues. The peptides PSF, IPG, CSG, … Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.