Sensitive Spectrophotometric Determination of Triprolidine Hydrochloride Drug in the Capsules via Ion Pair Complex Formation
Sameer Abdulrahman,
Jalal Qazzan
Abstract:The objective of this study was to develop two simple and selective visible spectrophotometric methods for the determination of antihistamine drug triprolidine hydrochloride (TRH) in the capsules. The methods were based on the formation of ion-pair complexes between TRH and two dyes, namely, bromocresol green (BCG) and bromophenol blue (BPB). The produced ion-pair complexes were measured at 415 and 410 nm for BCG and BPB methods, respectively. Beer’s law was applicable in the concentration ranges of 2.50-15.0 … Show more
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