Abstract:OPTIMIZATION AND VALIDATION OF A SIMPLE AND LOW-COST SEMI-QUANTITATIVE ENZYMATIC METHOD TO SEARCH FOR CISTEINE PROTEASES INHIBITORS. Cysteine proteases are an important class of enzymes involved in several essential biological processes. For this reason, these enzymes are important therapeutic targets, and therefore can be used in enzymatic assays for the search of hits. The most widely used methods in the search of enzyme inhibitors are spectrophotometric, however they have relatively high operational costs. … Show more
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