Extração Do Paracetamol E Análise Da Dispersão Da Massa De Comprimidos: Comparando Medicamentos Genérico E De Referência Em Laboratório De Ensino

Santana, Leandro D. de; Barboza, Orlando Maia; Barretto, Fernando Alves; Lopes, Wilson Araújo; Cunha, Sílvio

doi:10.21577/0100-4042.20170596

Quím. Nova

2020

DOI: 10.21577/0100-4042.20170596

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Extração Do Paracetamol E Análise Da Dispersão Da Massa De Comprimidos: Comparando Medicamentos Genérico E De Referência Em Laboratório De Ensino

Leandro D. de Santana

Orlando Maia Barboza

Fernando Alves Barretto

et al.

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2024

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Beyond Medicine: Paracetamol as Reagent in Multicomponent Synthesis of 1,3-Benzoxazine

Antonelli,

Mattos,

Victor

et al. 2024

J. Chem. Educ.

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A multicomponent reaction was adapted and successfully applied in the major organic course, which involves synthesizing and characterizing a 1,3-benzoxazine derived from paracetamol extracted from tablets of the worldwide well-known medicine Tylenol. Using paracetamol as a reagent is a motivational strategy in undergraduate laboratories to meet the learning goals of training students in solid–liquid extraction and compound characterization by NMR and FTIR and reaction mechanism discussions in the context of a multicomponent reaction. The multifaceted nature of this experiment encourages students to recognize the potential use of everyday materials as chemical reagents, while providing insights into modern chemistry concepts.

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Beyond Medicine: Paracetamol as Reagent in Multicomponent Synthesis of 1,3-Benzoxazine

Antonelli,

Mattos,

Victor

et al. 2024

J. Chem. Educ.

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show abstract

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Extração Do Paracetamol E Análise Da Dispersão Da Massa De Comprimidos: Comparando Medicamentos Genérico E De Referência Em Laboratório De Ensino

Cited by 1 publication

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Beyond Medicine: Paracetamol as Reagent in Multicomponent Synthesis of 1,3-Benzoxazine

Beyond Medicine: Paracetamol as Reagent in Multicomponent Synthesis of 1,3-Benzoxazine

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