Synergisms Between Metal and Photoredox Catalysis: Deconvoluting Complex Systems

Abstract

Recebido em 20/12/2019; aceito em 02/03/2020; publicado na web em 21/04/2020 This review briefly describes the evolution of organometallic chemistry and photoredox catalysis as independent fields; followed by a more in-depth presentation and discussion of representative examples derived from their synergistic combination, which generally leads to powerful cross-coupling protocols. In this context, the rational deconvolution of these complex catalytic systems into their isolated, more simple components are evaluated in order to understand their properties and reactivities.

Expanding the Synthetic Toolbox through Metal–Enzyme Cascade Reactions

“…3 In this field, multiple organometallic complexes and catalysts belong to the synthetic chemist toolbox, finding compounds from copper, iron, palladium, platinum, ruthenium, and zinc as the traditional choices, while others from gold, manganese, and nickel have emerged in the last decades as suitable and efficient catalysts. Currently, merging different catalytic processes for increasing molecular complexity is receiving great attention, metal catalysis presenting itself as a proper partner to be combined with photoredox 4 and biocatalytic transformations. 5−7 On the other hand, biocatalysis is nowadays considered a consolidated synthetic methodology, especially to obtain optically active products.…”