“…4 Second, the prognostic importance of quantifying the postoperative hemodynamic support requirement can also not be overemphasized in this peculiarly predisposed pediatric surgical subset. 5,6 Indeed, a multi-institutional analysis of the Pediatric Cardiac Critical Care Consortium (PC 4 ) by Gaies et al 6 delineated increased odds of poor composite outcome in infants with a high vasoactive-inotropic score (VIS) in the first 24 postoperative hours (OR: 6.5; 95% CI: 2.9-14.6, multivariable logistic regression pvalue = .001). Notably so, the VIS-poor outcome association continued to demonstrate significance post-stratification by age as well as surgical complexity.…”