Extracorporeal Membrane Oxygenation in COVID-19 Treatment: a Systematic Literature Review

Oliveira, Tatiana Farias de; Rocha, Carlos Alberto de Oliveira; Santos, Aisla Graciele Galdino dos; Silva, Luiz Carlos Francelino; Aquino, Saulo Henrique Salgueiro de; Cunha, Euclides José Oliveira da; Alcântara, Rafaela Campos; Mesquita, Rodrigo da Rosa; Arnozo, Gabriel Monteiro; Santana, Fernanda Mayara Santos; Filho, Etvaldo Rodrigues da Silva; Souza, Carlos Dornels Freire de

doi:10.21470/1678-9741-2020-0397

Cited by 10 publications

(5 citation statements)

References 14 publications

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“…The initial flow for ECMO-VA should be 50 to 70 ml per kilogram every one minute with a mean arterial pressure > 60 mmhg. [20] In ECMO-VA, blood ejected from the left ventricle is a mixture of venous blood supplied by the right ventricle and bronchial and pulmonary collateral blood flow. In the abnormal pulmonary gas exchange scenario, even when combined with fully oxygenated blood from the femoral arterial cannula, the blood that permeates the brain, heart and upper extremities can have a saturation below 90%, causing cyanosis in the upper body, a condition called harlequin.…”

Section: Resultsmentioning

confidence: 99%

Extracorporeal Membrane Oxygenation in the COVID-19 Pandemic

Assunção¹,

Santos²,

Oliveira³

et al. 2021

IJAERS

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Objective: This study aims to discuss the risks and benefits of ECMO in the treatment of patients with severe COVID-19. Method: This is a narrative review study of the literature with a qualitative approach, carried out in the PubMed, MEDLINE, LILACS, SciELO and Google Scholar databases in April 2021. Results: The analysis of the literature shows the importance of applying conventional treatment before opting for ECMO, and should be considered when other measures that have been

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Section: Resultsmentioning

confidence: 99%

Extracorporeal Membrane Oxygenation in the COVID-19 Pandemic

Assunção¹,

Santos²,

Oliveira³

et al. 2021

IJAERS

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“…In another systematic review [67] wich included 18 studies that analysed also the effect of ECMO on improving COVID-19 patients' outcomes, the authors concluded with the need for future research.…”

Section: P R E P R I N Tmentioning

confidence: 99%

The Use of Extracorporeal Membrane Oxygenation in COVID-19: a systematic review

Ionescu¹,

Zavalichi

Arsenescu-Georgescu

et al. 2023

Arch Med Sci

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IntroductionCOVID-19 pandemic represents a major worldwide challenge, with a great impact on health systems and economic mechanisms. SARS-CoV-2, the pathogen agent that generates COVID-19, creates a wide variety of organ dysfunctions, from acute respiratory distress syndrome (ARDS) to acute myocardial infarction or pulmonary embolism. Mechanical circulatory support devices such as Extracorporeal Membrane Circulatory Oxygenation (ECMO) have shown their efficacy in maintaining organs perfusion in respiratory and cardiac impairments. With this review, we aimed to assess the impact of ECMO use in COVID-19 patients with ARDS.Material and methodsWe performed a systematic review to find the studies using ECMO in COVID-19. Comorbidities, side effects, and survival rate to discharge were analysed. The literature search was done using PubMed/MEDLINE, Web of Science, Embase (Elsevier), the Cochrane Central Register of Controlled Trials (Wiley) and clinicaltrials.gov databases (inception (December 2019) to October 16, 2021), by 2 authors.ResultsWe included 33 studies from 10 countries with a total of 4.760 patients receiving ECMO for COVID-19. Survival rate varied from 9% to 90,6% at discharge. The most serious adverse events were acute kidney injury (up to 87%), major bleeding (up to 92,1%), strokes or cerebral hemorrhage (up to 34%). Other complications such as pulmonary embolism, peripheral bleeding, or sepsis had a major impact on survival rates.ConclusionsECMO in COVID-19 patients may be a useful rescue therapy instrument, but due to the great variability of studies and still unknown mechanisms and effects of the SARS-CoV-2, further studies are need to be done.

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“…Ketika terapi konvensional gagal, Extracorporeal Membrane Oxygenation (ECMO) dapat dipertimbangkan sebagai alternatif, mengatakan terapi pada ARDS akibat COVID-19 meliputi ventilasi mekanik, blokade neuromuskular, Positif End Expiarory Pressure (PEEP) yang lebih tinggi, teknik rekrutmen paru, dan posisi prone. Ketika terapi konvensional gagal, ECMO dapat menjadi alternatif terapi (De-Oliveira et al, 2021;Meyer et al, 2021).…”

Section: Pendahuluanunclassified

“…Mesin ECMO memompa darah dari tubuh pasien ke paru-paru buatan (oksigenator) dengan menambahkan oksigen dan mengeluarkan karbondioksida, kemudian mengirimkan darah kembali ke pasien melalui pompa dengan kekuatan yang sama seperti jantung (White et al, 2021). ECMO diindikasikan pada pasien dengan hipoksemia refrakter dengan tekanan parsial oksigen (PaO2/Fraksi Oksigen Inspirasi (FiO2) kurang dari 80 selama lebih dari 6 jam (De-Oliveira et al, 2021). Menurut Gulmez (2020) indikasi pemasangan ECMO diantaranya adalah insufisiensi pernapasan dengan rasio nilai PO2/FiO2 di bawah 100, penggunaan ventilasi mekanik kurang dari 7 hari, usia di bawah 65 tahun dan terdapat kontraindikasi seperti penggunaan antikoagulan yang lama (risiko perdarahan), memiliki komorbid yang banyak atau berat, penggunaan ventilasi mekanik lebih dari 14 hari.…”

Section: Pendahuluanunclassified

Aspek Caring Perawat dalam Perawatan Pasien ARDS COVID-19 Terpasang Extracorporeal Membrane Oxigenation (Ecmo): Studi Kasus dengan Pendekatan Teori Keperawatan Care, Core and Cure Lydia Hall

Elyas

Yona²,

Waluyo³

2022

JKS

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This study aims to provide an overview of nurses' caring in carrying out critical nursing care for Covid-19 patients installed with Extracorporeal Membrane Oxygenation (ECMO) in the ICU using the Care, Core, Cure Lydia Hall nursing theory. This type of research is qualitative research with a case study approach. The results showed that nursing problems that occurred in patients after ECMO installation included airway disorders, gas exchange disorders, bleeding risks, and the risk of impaired skin integrity due to decreased tissue perfusion. In conclusion, Lydia Hall's nursing theory is dominated by the Cure aspect because the installation of ECMO is a very complex medical procedure and involves teams from various disciplines. Hence, the implementation of the Cure aspect is a collaborative act of nurses. Care and Core aspects also have an essential role in caring for nurses, namely by conducting therapeutic interactions and facilitating patients to get family support so that patients have the spirit to recover and do not experience stress that can affect hemodynamic conditions. Keywords: COVID-19, ECMO, ICU, Lydia Hall, Case Study

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Extracorporeal Membrane Oxygenation in COVID-19 Treatment: a Systematic Literature Review

Cited by 10 publications

References 14 publications

Extracorporeal Membrane Oxygenation in the COVID-19 Pandemic

Extracorporeal Membrane Oxygenation in the COVID-19 Pandemic

The Use of Extracorporeal Membrane Oxygenation in COVID-19: a systematic review

Aspek Caring Perawat dalam Perawatan Pasien ARDS COVID-19 Terpasang Extracorporeal Membrane Oxigenation (Ecmo): Studi Kasus dengan Pendekatan Teori Keperawatan Care, Core and Cure Lydia Hall

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