The Importance of Intra-aortic Pulse Pressure After Anterior ST-segment Elevation Myocardial Infarction

Gül, İlker; Cerit, Levent; Şentürk, Bihter; Alkan, Mustafa; Kemal, Hatice; Cerit, Zeynep; Yaman, Belma; Usalp, Songül; Duygu, Hamza

doi:10.21470/1678-9741-2018-0106

Cited by 7 publications

(4 citation statements)

References 22 publications

(30 reference statements)

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“…For a long time, people have understood that inflammation may lead to coronary artery disease [CAD]. The prognosis and potential consequences in individuals with IHD are intimately linked to inflammation [12]. Atherosclerotic plaques may cause myocardial infarction [MI] if inflammation is severe enough [13].…”

Section: Discussionmentioning

confidence: 99%

Value of Immature Granulocyte in Prediction of Severity of Coronary Artery Disease and Short Term Outcome in Patients with Ischemic Heart Disease

E. Mansour,

E. El-Din El-Rbaat,

H. AbdeRahman

et al. 2024

Benha Journal of Applied Sciences

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Background: Ischemic Ischemic heart disease [IHD] is a leading cause of hospitalizations and visits to the emergency room. Rupture of atherosclerotic plaques and coronary artery thrombosis, either whole or partial, are typical symptoms of IHD. This research set out to compare the SYNTAX score [SX score] with the value of immature granulocyte in predicting the severity of coronary artery disease in ischemic heart disease patients having coronary angiography at Benha University. Included were 200 individuals who had coronary artery disease. Patients with cancer, inflammatory bowel disease, chronic renal failure, chronic liver failure, heart failure, being under the age of 18, pregnant, or using steroids or immunosuppressive drugs were excluded. The results showed that hypertension, heart rate, LDL and triglyceride levels, and HDL levels were all lower in patients with high granulocytes. The amount of granulocytes was significantly correlated with other inflammatory indicators [p value < 0.05]. Complex coronary vasculature and a high syntax score were both linked to a high granulocyte level.

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Section: Discussionmentioning

confidence: 99%

Value of Immature Granulocyte in Prediction of Severity of Coronary Artery Disease and Short Term Outcome in Patients with Ischemic Heart Disease

E. Mansour,

E. El-Din El-Rbaat,

H. AbdeRahman

et al. 2024

Benha Journal of Applied Sciences

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“…Neutrophils produce many proteolytic enzymes that cause tissue destruction, such as acid phosphatase, myeloperoxidase, and elastase [16][17][18]. Moreover, inflammation is highly associated with possible complications and prognosis of AMI [19]. Increasing the intensity of inflammation increases the likelihood of atherosclerotic plaque, which in turn causes MI [20].…”

Section: Discussionmentioning

confidence: 99%

Immature granulocyte in prediction of the short-term and long-term mortality of patients with acute myocardial infarction

GÜLTEN

ÇALIŞGAN

Akyel

et al. 2023

The European Research Journal

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Objectives: Despite great advances in the treatment of acute myocardial infarction (AMI), it is still the most common cause of death in the world. Therefore, predicting mortality in advance is clinically very important. In this study, we aimed to investigate the role of immature granulocyte (IG) and other hematological markers in predicting short- and long-term mortality in patients with AMI. Methods: Laboratory information system (LIS) data of a tertiary hospital were used in this study. Of the 298 patients who were admitted to the coronary intensive care unit with the diagnosis of myocardial infarction, 258 recovered after treatment and were discharged. 40 of them died. It was determined that 36 of these 258 patients, who were followed up retrospectively, died within 15 months after discharge. Results: The mean age of 298 people who participated in this retrospective study was 73.26 ± 8.6 years, and 53.3% were male. Moderate and high predictive property in receiver operating characteristic (ROC) analysis for short-term mortality, white blood cell (WBC) area under curve (AUC) = 0.802), neutrophil count (AUC = 0.817), IG count (AUC = 0.841), neutrophil/lymphocyte ratio (NLR) (AUC = 0.701), and C-reactive protein (CRP) (AUC = 0.758) tests detected. For long-term mortality, a moderate predictive feature was observed in the age (AUC = 0.712) parameter. Conclusions: IG is a marker that does not require extra cost, provides rapid results and has high predictive value in predicting death in the short term in patients with acute myocardial infarction. It is ineffective in predicting long-term mortality.

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“…The association between MI and inflammation has been known for many years. Furthermore, inflammation is closely associated with the prognosis and possible complications in patients with STEMI [ 14 ] . Increasing intensity of inflammation increases the likelihood that atherosclerotic plaques can lead to MI [ 15 ] .…”

Section: Discussionmentioning

confidence: 99%

Usefulness of Immature Granulocytes as A Prognostic Factor in ST-Elevation Myocardial Infarction

Korkut¹,

Bedel²,

Sivil³

et al. 2022

Braz J Cardiovasc Surg

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Objective ST-segment elevation myocardial infarction (STEMI) is a serious, life-threatening disease. Inflammatory markers have recently become the focus of attention in the assessment of severity in the early stages of STEMI. This study aimed to evaluate the importance of immature granulocytes (IG) as a prognostic marker in STEMI. Methods Patients admitted to the coronary care unit with a diagnosis of STEMI and who underwent primary percutaneous coronary intervention (pPCI) within the period from January 1, 2019 to January 1, 2020, were retrospectively scanned. A total of 146 patients were analised; of these, 112 (76.7%) were male and 34 (33.3) were female, with a mean age of 62.65±14.06 years. Patients’ age, gender, haemogram, biochemistry, and mortality results were recorded. The patients were divided into two groups as low (<0.6) and high (≥0.6) IG levels and compared. Results The mean IG levels were significantly higher in the non-survivor group compared to the survivor group (1.12±0.22 vs. 0.50±0.28, P<0.001). Mortality rates were significantly higher in the high IG group compared to the low IG group (26.9% vs. 9.6%, P=0.006). IG was shown to predict mortality with a sensitivity of 72.2% and a specificity of 77.8% at a cut-off value of 0.65 (area under the curve: 0.740, 95% CI: 0.635-0.846, P<0.001). Conclusion High IG values in the blood collected at the time of admission to the emergency department are a marker of mortality in patients with STEMI.

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The Importance of Intra-aortic Pulse Pressure After Anterior ST-segment Elevation Myocardial Infarction

Cited by 7 publications

References 22 publications

Value of Immature Granulocyte in Prediction of Severity of Coronary Artery Disease and Short Term Outcome in Patients with Ischemic Heart Disease

Value of Immature Granulocyte in Prediction of Severity of Coronary Artery Disease and Short Term Outcome in Patients with Ischemic Heart Disease

Immature granulocyte in prediction of the short-term and long-term mortality of patients with acute myocardial infarction

Usefulness of Immature Granulocytes as A Prognostic Factor in ST-Elevation Myocardial Infarction

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