Preventive Effect of Preoperative Vitamin D Supplementation on Postoperative Atrial Fibrillation

Cerit, Levent; Özçem, Barçın; Cerit, Zeynep; Duygu, Hamza

doi:10.21470/1678-9741-2018-0014

Cited by 28 publications

(28 citation statements)

References 24 publications

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“…Cerit et al Investigated the effects of preoperative vitamin D supplementation on postoperative AF development. According to this study, vitamin D has no impact on preventing postoperative AF in patients with insufficiency, but it helps to reduce postoperative AF in patients with a deficiency 22 .…”

Section: Discussionmentioning

confidence: 83%

Is there a seasonal feature of new onset atrial fibrillation after coronary artery bypass graft surgery?

Ada

Polat

2019

Cumhuriyet Medical Journal

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Atrial fibrillation (AF) is seen as very common after cardiac surgery. Postoperative AF occurrence increases mortality and morbidity. Deterioration of clinical condition of the patients results prolongation of hospital stay and increases economic burden. Many risk factors that have an impact on the development of postoperative AF are known. Low vitamin D level has been added to these factors in recent years. Blood serum levels of vitamin D is varied seasonally. Therefore, these factors can be expected to have a seasonal effect on development of postoperative AF. The aim of this study is to investigate the presence of annual features of postoperative AF. Method: This study is a retrospective analysis of patients who developed atrial fibrillation after coronary artery bypass graft surgery in the

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Section: Discussionmentioning

confidence: 83%

Is there a seasonal feature of new onset atrial fibrillation after coronary artery bypass graft surgery?

Ada

Polat

2019

Cumhuriyet Medical Journal

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“…Despite identification of important risk factors for AF, such as old age, arterial hypertension, HF, CAD, valvular heart disease, surgery, and hyperthyroidism, a significant fraction of its risk remains currently unexplained [ 71 ]. Recent studies showed that low vitamin D levels are associated with AF and may be implicated in its pathogenesis, thus suggesting the potential of vitamin D to also become a therapeutic target in this clinical setting [ 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 , 86 , 87 ].…”

Section: Vitamin D and Atrial Fibrillationmentioning

confidence: 99%

Vitamin D and Cardiovascular Disease: Current Evidence and Future Perspectives

et al. 2021

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Vitamin D deficiency is a prevalent condition, occurring in about 30–50% of the population, observed across all ethnicities and among all age groups. Besides the established role of vitamin D in calcium homeostasis, its deficiency is emerging as a new risk factor for cardiovascular disease (CVD). In particular, several epidemiological and clinical studies have reported a close association between low vitamin D levels and major CVDs, such as coronary artery disease, heart failure, and atrial fibrillation. Moreover, in all these clinical settings, vitamin deficiency seems to predispose to increased morbidity, mortality, and recurrent cardiovascular events. Despite this growing evidence, interventional trials with supplementation of vitamin D in patients at risk of or with established CVD are still controversial. In this review, we aimed to summarize the currently available evidence supporting the link between vitamin D deficiency and major CVDs in terms of its prevalence, clinical relevance, prognostic impact, and potential therapeutic implications.

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“…Oxidative stress, inflammation, and RAAS activation are the main mechanisms responsible for atrial fibrosis and might be associated with AF recurrence after ablation in patients with vitD deficiency [21] . Additionally, preoperative vitD supplementation could prevent postoperative AF after coronary artery bypass surgery [22] .…”

Section: Discussionmentioning

confidence: 99%

Is there any Link Between Vitamin D and Recurrence of Atrial Fibrillation after Cardioversion?

Yaman¹,

Cerit²,

Gunsel³

et al. 2020

Braz J Cardiovasc Surg

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Introduction: Atrial fibrillation (AF) is the most common chronic arrhythmia in the elderly population. In symptomatic patients, restoration and maintenance of sinus rhythm improve quality of life. Unfortunately, AF recurrence still occurs in a considerable number of patients after cardioversion (CV). In this study, we aimed to evaluate the association between vitamin D (VitD) and AF recurrence after electrical or medical CV. Method: A total of 51 patients who underwent CV for symptomatic AF were included in the study. AF recurrence was defined as an AF pattern in 12-lead electrocardiography (ECG) recording after CV within 6 months or ECG Holter recording of AF lasting more than 30 seconds at 6-month follow-up. Results: Mean vitD level was 21.4 ng/ml in our study population. VitD level was lower in the AF recurrence group than in the non-recurrence group (18 ng/ml vs. 26.3 ng/ml, respectively; P=0.001). Additionally, left atrial diameter was larger in the AF recurrence group compared to the non-recurrence group (4.4 vs. 4.1, P=0.025). Patients with AF recurrence were older than patients without AF recurrence, and, although the prevalence of hypertension is higher in the AF recurrence group, there was no statistically significant difference (P=0.107, P=0.867). Conclusion: In our study, there is a strong association between vitD level and AF recurrence after CV. VitD deficiency might be a predictor of high risk of AF recurrence after CV and vitD supplementation during the follow-up might help the maintenance of sinus rhythm.

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Preventive Effect of Preoperative Vitamin D Supplementation on Postoperative Atrial Fibrillation

Cited by 28 publications

References 24 publications

Is there a seasonal feature of new onset atrial fibrillation after coronary artery bypass graft surgery?

Is there a seasonal feature of new onset atrial fibrillation after coronary artery bypass graft surgery?

Vitamin D and Cardiovascular Disease: Current Evidence and Future Perspectives

Is there any Link Between Vitamin D and Recurrence of Atrial Fibrillation after Cardioversion?

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