Pulsatile gonadotropin releasing hormone therapy for spermatogenesis in congenital hypogonadotropic hypogonadism patients who had poor response to combined gonadotropin therapy
Zhenxing Huang,
Xi Wang,
Bingqing Yu
et al.
Abstract:Objective:
Both pulsatile gonadotropin-releasing hormone (GnRH) and combined gonadotropin therapy are effective to induce spermatogenesis in men with congenital hypogonadotropic hypogonadism (CHH). This study aimed to evaluate the effect of pulsatile GnRH therapy on spermatogenesis in male patients with CHH who had poor response to combined gonadotropin therapy.
Materials and methods:
Patients who had poor response to combined gonadotropin therapy ≥ 6 months were recrui… Show more
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