Prevalence of metabolic syndrome in adolescents based on three diagnostic definitions: a cross-sectional study

Abstract

Objective: There is no consensus as to the best criterion for the evaluation of metabolic syndrome (MS), impairing the estimation of its prevalence. This study aims to compare MS estimates using three recommended definitions for adolescents based on a cross-sectional study nested in the Consortium of Brazilian Birth Cohorts in São Luís, Maranhão. Subjects and methods: A total of 2,515 adolescents aged between 18 and 19 years were evaluated. The criteria of International Diabetes Federation (IDF) and National Cholesterol Education Program Panel III (NCEP-ATP) modified by Cook and cols. ( 2003) and De Ferranti and cols. ( 2004) defined SM. To compare the estimates of MS prevalence, the chi-square, Fisher's exact and Cohen's Kappa index tests were used. Results: Among the 2,064 participants evaluated in the final sample. The prevalence of MS ranged from 4.2% (95% CI: 3.3-5.1) to 10.2% (95% CI: 8.8-11.4). When comparing the estimates of MS prevalence in the total sample and by sex, a statistically significant difference was observed. The agreement between the criteria ranged from 0.42 (CI 95%: 0.35-0.49) to 0.55 (CI 95%: 0.48-0.62) in the total sample, 0.33 (CI 95%: 0.24-0.42) to 0.59 (95%CI: 0.47-0.71) among boys and 0.39 (95% CI: 0.26-0.52) to 0.54 (95% CI: 0.44-0.64) among girls. Conclusion: Different criteria provide different estimates for the prevalence of MS in adolescents, reflecting the importance of establishing a consensus.

Prevalence and correlates of metabolic syndrome among adults in Freetown, Sierra Leone: A comparative analysis of NCEP ATP III, IDF and harmonized ATP III criteria

“…However, the agreement between Harmonized ATP III and NCEP ATP III criteria was the best. The significant overlap among the MetS criteria in our study is not unexpected, as other studies have also reported similar findings in Nigeria, Brazil, India and Mongolia [ 26 , [55] , [56] , [57] ]. Even though MetS has been extensively researched in the last decade, public awareness is limited in most LMIC and industrial countries.…”

Prevalence and correlates of Metabolic Syndrome among adults in Freetown, Sierra Leone: A comparative analysis of NCEP ATP III, IDF and Harmonized ATP III criteria

“…Harmonised ATP III and NCEP ATP III criteria appeared to be the best. The significant overlap among the MetS criteria in our study is not unexpected, as other studies have also reported similar findings in Nigeria, Brazil, India and Mongolia [34,[55][56][57]. Even though MetS has been extensively researched in the last decade, public awareness is limited in most LMIC and industrial countries.…”

Metabolic syndrome: a population-based study of prevalence and risk factors

“…Other studies evaluating definitions of MetS in youth reported variations from 2.7 to 3.8% 35 and from 0.3 to 26.4% 36 . Melo et al, in 2023 showed that different criteria provide different estimates for the prevalence of MetS in adolescents and youth, reflecting the importance of establishing a consensus 37 . Findings by Nolan’s study (a pooled analysis) highlighted that MetS was prevalent in young adults (18–30 years old) at about 4.8% (NCEP-ATPIII) and 7.0% (International IDF) 4 .…”