Restricted feeding modulates peripheral clocks and nutrient sensing pathways in rats

Rodrigues, Luis Guilherme F.; Araújo, Leonardo Domingues de; Roa, Silvia Liliana Ruiz; Bueno, Ana Carolina; Uchôa, Ernane Torres; Antunes‐Rodrigues, José; Moreira, Ayrton Custódio; Elias, Lucila Leico Kagohara; Castro, Margaret de; Martins, Clarissa Silva

doi:10.20945/2359-3997000000407

Cited by 2 publications

(1 citation statement)

References 36 publications

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“…Aligning meal times with the circadian rhythms by time-restricted feeding in animal models can also modulate PGC1α activity and mitochondrial biogenesis. [ 323 , 349 , 350 , 351 , 352 , 353 ]. Additionally, various polyphenolic compounds contribute to mitochondrial biogenesis via PGC1α activation, which is mediated via AMPK-SIRT1 activation [ 354 , 355 ].…”

Section: Mechanisms Of Chrononutrition In Energy Homeostasis and Obesitymentioning

confidence: 99%

Chrononutrition—When We Eat Is of the Essence in Tackling Obesity

Ahluwalia

2022

Nutrients

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Obesity is a chronic and relapsing public health problem with an extensive list of associated comorbidities. The worldwide prevalence of obesity has nearly tripled over the last five decades and continues to pose a serious threat to wider society and the wellbeing of future generations. The pathogenesis of obesity is complex but diet plays a key role in the onset and progression of the disease. The human diet has changed drastically across the globe, with an estimate that approximately 72% of the calories consumed today come from foods that were not part of our ancestral diets and are not compatible with our metabolism. Additionally, multiple nutrient-independent factors, e.g., cost, accessibility, behaviours, culture, education, work commitments, knowledge and societal set-up, influence our food choices and eating patterns. Much research has been focused on ‘what to eat’ or ‘how much to eat’ to reduce the obesity burden, but increasingly evidence indicates that ‘when to eat’ is fundamental to human metabolism. Aligning feeding patterns to the 24-h circadian clock that regulates a wide range of physiological and behavioural processes has multiple health-promoting effects with anti-obesity being a major part. This article explores the current understanding of the interactions between the body clocks, bioactive dietary components and the less appreciated role of meal timings in energy homeostasis and obesity.

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Section: Mechanisms Of Chrononutrition In Energy Homeostasis and Obesitymentioning

confidence: 99%

Chrononutrition—When We Eat Is of the Essence in Tackling Obesity

Ahluwalia

2022

Nutrients

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Different Types of Glucocorticoids to Evaluate Stress and Welfare in Animals and Humans: General Concepts and Examples of Combined Use

et al. 2023

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The main glucocorticoids involved in the stress response are cortisol and cortisone in most mammals and corticosterone in birds and rodents. Therefore, these analytes are currently the biomarkers more frequently used to evaluate the physiological response to a stressful situation. In addition, “total glucocorticoids”, which refers to the quantification of various glucocorticoids by immunoassays showing cross-reactivity with different types of glucocorticoids or related metabolites, can be measured. In this review, we describe the characteristics of the main glucocorticoids used to assess stress, as well as the main techniques and samples used for their quantification. In addition, we analyse the studies where at least two of the main glucocorticoids were measured in combination. Overall, this review points out the different behaviours of the main glucocorticoids, depending on the animal species and stressful stimuli, and shows the potential advantages that the measurement of at least two different glucocorticoid types can have for evaluating welfare.

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Restricted feeding modulates peripheral clocks and nutrient sensing pathways in rats

Cited by 2 publications

References 36 publications

Chrononutrition—When We Eat Is of the Essence in Tackling Obesity

Chrononutrition—When We Eat Is of the Essence in Tackling Obesity

Different Types of Glucocorticoids to Evaluate Stress and Welfare in Animals and Humans: General Concepts and Examples of Combined Use

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