Polycystic ovary syndrome: new insights on the puzzle of adiposity, chronic low-grade inflammation and metabolic disturbances

Esfehani

et al. 2023

J Health Popul Nutr

Introduction Premenstrual syndrome (PMS) is a common condition that affects social and psychological well-being of women. The risk of PMS is higher among obese women. The aim of this study was to identify the factors that influence the severity of PMS in women with central obesity. Materials and methods This cross-sectional study was performed on 30–50 year-old women with abdominal obesity (waist circumference > 80 cm). The following data were collected: demographic data, anthropometric measurements, premenstrual symptoms screening tools, semi-quantitative food frequency questionnaire, 42-item depression, anxiety, and stress questionnaire (DASS-42), as well as serum vitamin D, and renal function tests. Results A total of 139 women (mean age of 41.40 ± 7.39 years old) participated in the study. The prevalence of mild, moderate and severe premenstrual symptoms was 38.7% (55/142), 31.7% (45/142) and 27.5% (39/142), respectively. There was no significant difference between the groups in terms of anthropometric measurements and energy-adjusted nutrient intakes (p > 0.05). There was a significant relationship between moderate PMS and energy-adjusted saturated fatty acid (SFA) (p = .018, OR = .010 and 95% CI for OR: < .001 and .452), and energy-adjusted riboflavin (p = .042, OR = .005, 95% CI for OR: < .001 and .821), and between severe PMS and age (p = .034, OR = .906, 95% CI for OR: .826 and .993), and energy-adjusted monounsaturated fatty acid (MUFA) intake (p = .041, OR = 23.789, 95% CI for OR: 1.138 and 497.294). Conclusion High intakes of MUFA and younger age were associated with a greater severity of PMS, while riboflavin intake was associated with reduced PMS severity.

Section: Data Collection and Questionnairesmentioning

confidence: 99%

“…The prevalence of PMS is high among women PCOS [ 22 ]. Obesity is also associated with inflammation, which might be associated with PMS [ 23 , 24 ]. It was previously shown that women with mood disorders, or PMS consumed more carbohydrate-rich foods, which may result in adiposity [ 10 , 25 , 26 ].…”

Section: Introductionmentioning

confidence: 99%

Factors associated with the severity of premenstrual symptoms in women with central obesity: a cross-sectional study

Esfehani

et al. 2023

J Health Popul Nutr

“…Items were scored based on a four-point scale (not at all=0, mild=1, moderate=2, severe=3). The severity of the premenstrual symptoms is categorized based on the sum of PSST scores into mild (0-19), moderate (19)(20)(21)(22)(23)(24)(25)(26)(27)(28), and severe (>28).…”

Section: Data Collection and Questionnairesmentioning

confidence: 99%

“…The prevalence of PMS is high among women with PCOS [21]. Obesity is also associated with in ammation, which might be associated with PMS [22,23]. It was previously shown that women with mood disorders, or PMS consumed more carbohydrate rich foods.…”

Section: Introductionmentioning

confidence: 99%

Factors associated with the severity of premenstrual symptoms in women with central obesity: a cross sectional study

Esfahani

et al. 2022

Preprint

Introduction: Premenstrual syndrome (PMS) is a common condition that affects social and psychological well-being of women. The risk of PMS is higher among obese women. The aim of this study was to identify the factors that influence the severity of PMS in women with central obesity.Materials and methods: This cross-sectional study was performed on women who were 30 to 50-year-old with abdominal obesity (waist circumference > 80cm). The following data were collected: demographic data, anthropometric measurements, premenstrual symptoms screening tools (PSST), semi-quantitative food frequency questionnaire (FFQ), 42-item depression, anxiety, and stress questionnaire (DASS-42), as well as serum vitamin D, and renal function tests. Results: A total of 139 women (mean age of 41.40 ± 7.39 years old) participated in the study. The prevalence of mild, moderate and severe premenstrual symptom was 38.7% (55/142), 31.7% (45/142) and 27.5% (39/142), respectively. There was no significant difference between the groups in terms of anthropometric measurements and energy-adjusted nutrient intakes (p>0.05). There was a significant relationship between moderate PMS and energy-adjusted SFA (p=.018, OR=.010 and 95% CI for OR: <.001 and .452), and energy-adjusted riboflavin (p=.042, OR=.005, 95% CI for OR: <.001 and .821) and between severe PMS and age (p=.034, OR=.906, 95% CI for OR: .826 and .993), and energy-adjusted monounsaturated fatty acid (MUFA) intake (p=.041, OR=23.789, 95% CI for OR: 1.138 and 497.294). Conclusions: High intakes of MUFA and younger age were associated with a greater severity of PMS, while riboflavin intake was associated with reduced PMS severity.

“…The prevalence of PMS is high among women PCOS (22). Obesity is also associated with in ammation, which might be associated with PMS (23,24). It was previously shown that women with mood disorders, or PMS consumed more carbohydrate rich foods, which may result in adiposity (10,25,26).…”

Section: Introductionmentioning

confidence: 99%

Factors associated with the severity of premenstrual symptoms in women with central obesity: a cross sectional study

Esfahani

et al. 2022

Preprint

Introduction: Premenstrual syndrome (PMS) is a common condition that affects social and psychological well-being of women. The risk of PMS is higher among obese women. The aim of this study was to identify the factors that influence the severity of PMS in women with central obesity. Materials and methods: This cross-sectional study was performed on 30 to 50-year-old women who were 30 to 50-year-old with abdominal obesity (waist circumference > 80cm). The following data were collected: demographic data, anthropometric measurements, premenstrual symptoms screening tools (PSST), semi-quantitative food frequency questionnaire (FFQ), 42-item depression, anxiety, and stress questionnaire (DASS-42), as well as serum vitamin D, and renal function tests. Results: A total of 139 women (mean age of 41.40 ± 7.39 years old) participated in the study. The prevalence of mild, moderate and severe premenstrual symptoms was 38.7% (55/142), 31.7% (45/142) and 27.5% (39/142), respectively. There was no significant difference between the groups in terms of anthropometric measurements and energy-adjusted nutrient intakes (p>0.05). There was a significant relationship between moderate PMS and energy-adjusted saturated fatty acid (SFA) (p=.018, OR=.010 and 95% CI for OR: <.001 and .452), and energy-adjusted riboflavin (p=.042, OR=.005, 95% CI for OR: <.001 and .821), and between severe PMS and age (p=.034, OR=.906, 95% CI for OR: .826 and .993), and energy-adjusted monounsaturated fatty acid (MUFA) intake (p=.041, OR=23.789, 95% CI for OR: 1.138 and 497.294). Conclusions: High intakes of MUFA and younger age were associated with a greater severity of PMS, while riboflavin intake was associated with reduced PMS severity.