The Human Host Defense Peptide LL-37 Overexpressed in Lung Cell Lines by Methanolic Extract of Valeriana officinalis

Mohammadi, Zinat; Pishkar, Leila; Eftekhari, Zohre; Barzin, Giti; Babaeekhou, Laleh

doi:10.1590/s2175-97902023e21025

Cited by 1 publication

(1 citation statement)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Despite its common use to treat anxiety and insomnia, Passiflora has a compound named Vitexin (apigenin-8-C-β-D-glucopyranoside), a flavone glycoside, which has demonstrated efficacy in reducing pulmonary edema and protein concentration in the alveoli [ 142 ]. Valerian extract has been found to modulate LL-37 gene and protein expression in lung cells, thus enhancing the immune system’s response to respiratory infections, including COVID-19 [ 143 ]. Additionally, Arnica exhibits bronchodilator activity like salbutamol, a well-known antiasthmatic medication [ 144 ].…”

Section: Commercially Available Important Plants In Mexicomentioning

confidence: 99%

Plants from Arid and Semi-Arid Zones of Mexico Used to Treat Respiratory Diseases: A Review

Dávila-Rangel,

Charles-Rodríguez,

López-Romero

et al. 2024

Plants

View full text Add to dashboard Cite

Medicinal plants have been a traditional remedy for numerous ailments for centuries. However, their usage is limited due to a lack of evidence-based studies elucidating their mechanisms of action. In some countries, they are still considered the first treatment due to their low cost, accessibility, and minor adverse effects. Mexico is in second place, after China, in inventoried plants for medicinal use. It has around 4000 species of medicinal plants; however, pharmacological studies have only been carried out in 5% of its entirety. The species of the Mexican arid zones, particularly in semi-desert areas, exhibit outstanding characteristics, as their adverse growing conditions (e.g., low rainfall and high temperatures) prompt these plants to produce interesting metabolites with diverse biological activities. This review explores medicinal plants belonging to the arid and semi-arid zones of Mexico, focusing on those that have stood out for their bioactive potential, such as Jatropha dioica, Turnera diffusa, Larrea tridentata, Opuntia ficus-indica, Flourensia cernua, Fouquieria splendes, and Prosopis glandulosa. Their extraction conditions, bioactive compounds, mechanisms of action, and biological efficacy are presented, with emphasis on their role in the treatment of respiratory diseases. Additionally, current research, novel applications, and perspectives concerning medicinal plants from these zones are also discussed.

show abstract

Section: Commercially Available Important Plants In Mexicomentioning

confidence: 99%