Hospital readmission within 30 days of older adults hospitalized in a public hospital

Abstract

Older adults have difficulty monitoring their drug therapy in the first thirty days following hospital discharge. This transition care period may trigger hospital readmissions. The study aims to identify the factors associated with the readmission of older adults 30 days after discharge from the perspective of drug therapy. This is a cross-sectional study and hospital admission within 30 days was defined as readmission to any hospital 30 days after discharge. The complexity of the drug therapy was established by the Medication Regimen Complexity Index (MRCI).. Readmission risks were predicted by the "Readmission Risk Score -RRS". The multivariate logistic regression was used to identify factors associated with readmission within 30 days after discharge. Two hundred fifty-five older adults were included in the study, of which 32 (12.5%) had non-elective hospital readmission. A higher number of readmissions was observed with increased RRS value, suggesting a linear gradient effect. The variables included in the final logistic regression model were the diagnosis of cancer (OR=2.9, p=0.031), pneumonia (OR=2.3, p=0.055), and High MRCI (> 16.5) following discharge (OR=1.9, p=0.119). The cancer diagnosis is positively associated with hospital readmissions of older adults within 30 days.

Adverse reactions to antimicrobials in pediatric patients admitted to a tertiary hospital: a cohort study

“…The length of stay is related to the characteristics of the hospital, the population served and the type and severity of the disease 4. The longer the hospital stay, the greater the exposure to medications and, consequently, the greater risk of developing ADRs, medication errors, microbial resistance, nosocomial infection and hospitalisation costs 7…”

“…The WHO defines adverse drug reaction (ADR) as "a harmful, unintentional response to a drug that occurs in doses normally used by humans for prophylaxis, diagnosis, treatment or modification of physiological function” 3. Factors such as exposure to multiple drugs, increased frequency and dose of drug administration, use of general anaesthesia, cancer diagnosis, age, sex and length of hospital stay are related to the development of ADRs in this population 4–6. The incidence of ADR in pediatric patients ranges from 0.6–16.8%.…”