Organic selenium supplementation is cost-effective for increasing the number of seminal doses produced by sexually mature boars

Martins, Simone Maria Massami Kitamura; Afonso, Esther Ramalho; Parazzi, Larissa José; Andrade, André Furugen Cesar de; Leal, Diego Feitosa; Gameiro, Augusto Hauber; Moretti, Aníbal de Sant’Anna; Arruda, Rubens Paes de

doi:10.1590/rbz4720160328

Cited by 3 publications

(7 citation statements)

References 16 publications

(26 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Besides, recently in an interesting cost–benefit analysis [109], it has been shown that boars fed organic Se-based (0.5 mg per kg) diet produced around 23% higher doses of semen per week compared to those maintained on inorganic Se diets (0.5 mg per kg). A significant increase in revenue (26%) was also observed in this study [109]. In any case, additional animal studies reporting the effects of Se supplementation on the male reproductive efficiency in different animal models are presented in Table 4.…”

Section: Role Of Selenium In Male Reproductionmentioning

confidence: 99%

Role of Selenium and Selenoproteins in Male Reproductive Function: A Review of Past and Present Evidences

et al. 2019

View full text Add to dashboard Cite

Selenium (Se) is an important trace mineral having many essential roles at the cellular and organismal levels in animal and human health. The biological effects of Se are mainly carried out by selenoproteins (encoded by 25 genes in humans and 24 in mice). As an essential component of selenoproteins, Se performs structural and enzymic roles; in the latter context it is well known for its catalytic and antioxidative functions. Studies involving different animal models have added great value to our understanding regarding the potential implications of Se and selenoproteins in mammalian fertility and reproduction. In this review, we highlight the implications of selenoproteins in male fertility and reproduction followed by the characteristic biological functions of Se and selenoproteins associated with overall male reproductive function. It is evident from observations of past studies (both animal and human) that Se is essentially required for spermatogenesis and male fertility, presumably because of its vital role in modulation of antioxidant defense mechanisms and other essential biological pathways and redox sensitive transcription factors. However, bearing in mind the evidences from mainstream literature, it is also advisable to perform more studies focusing on the elucidation of additional roles played by the peculiar and canonical selenoproteins i.e., glutathione peroxidase 4 (GPX4) and selenoprotein P (SELENOP) in the male reproductive functions. Nevertheless, search for the elucidation of additional putative mechanisms potentially modulated by other biologically relevant selenoproteins should also be included in the scope of future studies. However, as for the implication of Se in fertility and reproduction in men, though a few clinical trials explore the effects of Se supplementation on male fertility, due to inconsistencies in the recruitment of subjects and heterogeneity of designs, the comparison of such studies is still complicated and less clear. Therefore, further research focused on the roles of Se and selenoproteins is awaited for validating the evidences at hand and outlining any therapeutic schemes intended for improving male fertility. As such, new dimensions could be added to the subject of male fertility and Se supplementation.

show abstract

Section: Role Of Selenium In Male Reproductionmentioning

confidence: 99%

Role of Selenium and Selenoproteins in Male Reproductive Function: A Review of Past and Present Evidences

et al. 2019

View full text Add to dashboard Cite

show abstract

“…After 45 days of Se supplementation, the semen ejaculate volume, sperm motility and viability were significantly higher in Se supplemented diet compared to the control group; organic Se had a much faster effect compared to inorganic Se [ 144 ]. In addition, a recent study reported that boars fed on organic Se-based diet (0.5 mg per kg) determined a 23% increase in the sperm concentration per week compared to inorganic Se-based diet (0.5 mg per kg) [ 145 ]. Thus, clearly there is marked improvement in the structural and functional factors that define male fertility and sperm functions (refer to Figure 3 ), but questions on the precise dose, optimal form of Se, and duration of safe supplementation remain unanswered and warrants further research.…”

Section: Selenium and Male Reproductionmentioning

confidence: 99%

Role for Selenium in Metabolic Homeostasis and Human Reproduction

Mojadadi

Salah

et al. 2021

Nutrients

View full text Add to dashboard Cite

Selenium (Se) is a micronutrient essential for life. Dietary intake of Se within the physiological range is critical for human health and reproductive functions. Selenium levels outside the recommended range have been implicated in infertility and variety of other human diseases. However, presently it is not clear how different dietary Se sources are processed in our bodies, and in which form or how much dietary Se is optimum to maintain metabolic homeostasis and boost reproductive health. This uncertainty leads to imprecision in published dietary guidelines and advice for human daily intake of Se and in some cases generating controversies and even adverse outcomes including mortality. The chief aim for this review is to describe the sources of organic and inorganic Se, the metabolic pathways of selenoproteins synthesis, and the critical role of selenprotenis in the thyroid gland homeostasis and reproductive/fertility functions. Controversies on the use of Se in clinical practice and future directions to address these challenges are also described and discussed herein.

show abstract

“…It was observed an increase of 23% in semen AI-doses production, resulting in a 37% reduction in the cost of diet per dose produced by boars fed SeMet compared to that fed sodium selenite. The authors pointed out that the total revenue produced by the organic group was 26% higher than the inorganic one (MARTINS et al, 2014(MARTINS et al, , 2018.…”

Section: Organic Selenium In Boar Reproductionmentioning

confidence: 99%

“…From the results obtained in two semen evaluations, an average per characteristic was calculated. An indicator (score) represented these values' sum and allowed the animal ranking (I) according to Martins et al (2018).…”

Section: Distribution Of Animals Into Experimental Groupsmentioning

confidence: 99%

“…In pigs, when comparing the use of different selenium sources on boar reproduction, precisely sodium selenite (inorganic) vs. selenomethionine (SeMet; organic) via seleniumenriched yeast (Se-yeast), there are controversial results. While a range of studies reported benefits in favor of the organic form (SPEIGHT et al, 2012;MARTINS et al, 2014MARTINS et al, , 2018PETRUJKIĆ et al, 2014;WHITAKER, 2017), others suggested that organic and inorganic forms are equivalent (LOVERCAMP et al, 2013;MARTINS et al, 2015) or even that SeMet can negatively affect sperm quality (LÓPEZ et al, 2010). The lack of information about the selenium concentration in the basal diet offered to the animals, and the well-known variation in SeMet concentration delivered by commercial Se-yeast (a range from 21 to 70%), may contribute to different findings (SURAI; FISININ, 2015;GERAERT et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

>b<Effect of organic selenium on the cooled boar semen quality and reproductive performance>/b<

Pavaneli¹

View full text Add to dashboard Cite

O selênio é um micromineral essencial para o desenvolvimento e maturação dos espermatozoides, atuando como modulador da produção e qualidade espermática, e fertilidade masculina. Na espécie suína, fontes inorgânicas de selênio como o selenito de sódio (SS) têm sido ainda amplamente utilizadas para a suplementação das dietas, visando atender as exigências nutricionais de cada uma das categorias dentro do sistema de produção.Considerando a maior biodisponibilidade das fontes orgânicas, o presente estudo buscou avaliar o uso da hidróxi-selenometionina (OH-SeMet) na dieta de cachaços, uma fonte pura e orgânica de selênio, sobre as características seminais e performance reprodutiva dos animais. Avaliouse também dois níveis de inclusão de OH-SeMet. Para isso, 42 cachaços de raça pura (Landrace e Large-White) com idades entre 8 e 31 meses foram alimentados com os seguintes tratamentos por 95 dias: 0,3 mg selênio/kg via SS (n = 14); 0,3 mg selênio/kg via OH-SeMet (n = 14); e 0,6 mg selênio/kg via OH-SeMet (n = 14). Neste período, dois experimentos foram conduzidos concomitantemente. No experimento 1, o sêmen in natura foi avaliado quanto ao volume, concentração, motilidade e morfologia espermática, e atividade da enzima glutationa peroxidase (GPx) em plasma seminal. Doses inseminantes foram processadas, armazenadas a 17 ºC por 72 h, e após isso, avaliadas quanto à qualidade espermática (motilidade, morfologia, integridade de membranas, e resistência ao estresse oxidativo). Quantificou-se ainda, a concentração de selênio no plasma seminal e sanguíneo dos animais. As coletas de sêmen aconteceram semanalmente, enquanto as análises experimentais foram conduzidas a cada 2 semanas, totalizando 7 pontos de avaliação durante o estudo. No experimento 2, um total de 1131 fêmeas de raça pura (Landrace e Large-White) foi inseminado com doses provenientes dos diferentes tratamentos para avaliação de taxa de prenhez (TP) e características de leitegada.As inseminações aconteceram ao longo de todo o período experimental (95 dias), com doses sendo enviadas às granjas semanalmente. Os efeitos de fonte (SS vs. OH-SeMet) e de nível de suplementação orgânica (0,3 vs. 0,6 mg selênio/kg) foram avaliados em ambos os experimentos.Cachaços alimentados com OH-SeMet apresentaram maior concentração de selênio no plasma seminal (p < 0,05), bem como tenderam (p < 0,10) para uma maior contagem espermática no ejaculado (66,6 vs. 56,57 × 10 9 ) e, consequentemente, para um maior número de doses produzidas (22,11 vs. 18,85). Nenhum efeito foi observado sobre a concentração de selênio no plasma sanguíneo, atividade da GPx no plasma seminal, e qualidade espermática no sêmen in natura e refrigerado (p > 0,05). Nas granjas, doses inseminantes do grupo OH-SeMet resultaram em maior TP (99,3 vs. 97%) e menor porcentagem de natimortos (5,87 vs. 7,11%) (p < 0,05). Quanto ao uso de diferentes níveis de suplementação com a OH-SeMet, não foi observada qualquer diferença entre os valores estudados (p > 0,05). Como conclusão, a substituição de SS por OH-SeMet na dieta ...

show abstract

Organic selenium supplementation is cost-effective for increasing the number of seminal doses produced by sexually mature boars

Cited by 3 publications

References 16 publications

Role of Selenium and Selenoproteins in Male Reproductive Function: A Review of Past and Present Evidences

Role of Selenium and Selenoproteins in Male Reproductive Function: A Review of Past and Present Evidences

Role for Selenium in Metabolic Homeostasis and Human Reproduction

>b<Effect of organic selenium on the cooled boar semen quality and reproductive performance>/b<

Contact Info

Product

Resources

About