INTRODUCTION: Oral Health, like general health, is a basic fundamental right for all, and even more so for the underprivileged. AIM: To evaluate the oral health status of Institutionalized orphans aged 6-12 years and non-orphans in Indore, Madhya PradeshMATERIALS AND METHODS: The present descriptive cross-sectional study was conducted among various registered orphanages in Indore, Madhya Pradesh. Oral Examination was done by two standardized examiners (ADA type III examination) and data was entered using a pre-tested and pre-validated proforma. Data was transferred into MS excel and after application of descriptive statistics, the independent samples t-test and multiple logistic regression were applied (p value significant at ≤ 0.5). RESULTS: Of the total 263 study subjects, there were 132(50.2%) orphans and 131(49.8%) school children aged 6-12 years. Among orphans, males (62.9%) formed the majority; use of toothbrush with toothpaste was observed among 69.7% of orphans, while 6.1% did not use any oral hygiene aid. The most common observed hard lesion was dental caries (31.8%) as compared to 20.6% in school children and its presence revealed a significant association (p=0.02). CONCLUSION: It is recommended that a special emphasis should be made to promote oral health among the children residing in orphanages.