Effects of catalpa seed oil and pomegranate seed oil on body weight and intestinal flora in mice

Abstract

This study investigated the effects of different concentrations of catalpa seed oil (CSO) and pomegranate seed oil (PSO) on body weight and intestinal flora in mice. The results showed that the addition of 10% w/t CSO or PSO had a more significant effect than control (soybean oil) on reducing the body mass index of mice, which was reduced by 24.94% ± 0.08% (p < 0.01) and 25.88% ± 0.11% (p < 0.01), respectively. Histological observations indicated that no significant changes in the development and structure of mouse intestinal tissue were detected as a result of CSO and PSO. Using bioinformatics technology, CSO and PSO were used to study the clustering of operational taxonomic units and the relative abundance of microorganisms in intestinal bacteria. The analysis found that both functional lipids could reduce the relative abundance of γ-Proteobacteria. It is suggested that CSO and PSO have a regulatory effect on the structure of intestinal microflora in mice. The development reported in this paper provided theoretical support for the functional research and in-depth development of CSO and PSO.

Hyperuricemia research progress in model construction and traditional Chinese medicine interventions

“…This protein lowers UA levels and protects the kidney. Wang et al (2022) established an HUA rat model using adenine and PO to evaluate the anti-HUA efficacy of poria powder. They found that poria powder significantly improved renal function, glomerular atrophy, and renal tubule dilation in HUA rats.…”

Integrative Approach to Gastrointestinal Wellness: Efficacy of a Traditional Chinese Herbal Tea Formula Containing Hemp Seed

“…The mixture of hemp seed oil and water could induce changes in the intestinal flora of mice, increase the proportion of Bacteroidetes and decrease the proportion of Firmicutes, and improve the biodiversity of intestinal bacterial community in mice [24] . The research findings have also demonstrated that hemp seed oil can increase the levels of acetic acid and butyric acid and relieve constipation [25] .…”

Revealing the effect of sea buckthorn oil, fish oil and structured lipid on intestinal microbiota, colonic short chain fatty acid composition and serum lipid profiles in vivo

“…Functional oil plays a vital role in the human diet due to its abundant bioactive substances [ 1 ]. Dietary fat is an important part of the human diet, and its nutritional value is largely determined by its fatty acid composition, which is closely related to human health [ 2 ].…”

“…Imbalances in the structure of the intestinal microbiota can have an impact on the host's metabolic and circulatory systems, with fatty acids playing a significant role as part of gut metabolites [ 21 ]. For example, imbalances in the intestinal microbiota have been associated with inflammatory bowel disease, colorectal cancer, obesity, diabetes, atherosclerosis, and liver disease [ 1 , 21 – 24 ]. It is widely recognized that diet plays a major role in influencing the composition and function of the human intestinal microbiota which regulates various immune functions within the body.…”