Baicalein regulates NEDD4L-mediated TLR2 ubiquitination to relieve Mycobacterium tuberculosis-induced pneumonia in mice

Abstract

Online)M. tb mainly exists in antigen-presenting cells in the host, including macrophages and dendritic cells, and evades the body's immune defenses by inhibiting the secretion of MHC class II molecules and preventing antigen presentation (Repique et al., 2003). In this process, the glycolipids on the cell wall surface of M. tb, including lipoarabinomannan (LAM), lipomannan (LM)