Physicochemical and antioxidant properties of methanol extract from Maca (Lepidium meyenii Walp.) leaves and roots

Medicinal plants are valuable natural sources for the development of potentially safe drugs. The biological activities associated with these plants are due to the presence of certain phytochemicals that act individually or synergistically. Thus, this study examined the phytochemical components, antioxidant and antimicrobial activities of n-hexane, ethylacetate and methanolic extracts of Pennisetum purpureum (Schumach). Qualitative and quantitative phytochemical assays of P. purpureum showed the presence of alkaloids (0.004%), saponins (0.002%), flavonoids (0.021%), steroids, terpenoids and glycosides (0.008%). Methanol, n-hexane and ethylacetate extracts of P. purpureum were examined for antimicrobial activity using the disc diffusion method. Six microbial strains were exposed to six different concentrations of each extracts; 200 mg/ml, 100 mg/ml, 50 mg/ml, 25 mg/ml, 12.5 mg/ml and 6.25 mg/ml. The three extracts demonstrated varied concentration-dependent antimicrobial activities against the test organisms. The methanolic extract showed antibacterial activity against E. coli, S. aureus, B. cereus and antifungal activity against T. mentagrophyte and A. niger. Among all extracts, the methanolic extract of P. purpureum exhibited relatively strong antifungal activity against A. niger (10.3±0.12 mm) when compared to the standard antifungal agent, fluconazole (13.9±0.12 mm). Furthermore, antioxidant activities were spectrophotometrically studied using vitamin C as standard; methanol and ethylacetate extracts of P. purpureum showed pronounced scavenging activity on 2,2-diphenyl-1-picrylhydrazyl (DPPH); and had a potent reductive ability on ferric ion and phosphomolybdate. However, only the non-polar extract of P. purpureum showed a non-significant correlation and significant differences when compared to vitamin C. Antioxidant activities of the plant extracts were observed in the order of methanol >ethylacetate> n-hexane extracts. The results showed that P. purpureum contains phytochemicals that significantly contributed to the observed antimicrobial and antioxidant abilities of the plant and could be used as a potential source for the development of novel therapeutic drugs.

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“…2). This result is consistent with another report of a strong correlation of antioxidant activity in methanolic extract [57].…”

Section: Dpph Radical Scavenging Activitysupporting

confidence: 94%

Evaluation of Phytochemical, Antimicrobial and Antioxidant Capacities of Pennisetum purpureum (Schumach) Extracts

Jack

Clark

Ndukwe

2020

CSIJ

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“…Because of its unique nutritional and phytochemical composition, Maca is considered a “super food” [ 95 , 111 , 153 ]. Different Maca extracts, such as the tuber and starch, are used as food [ 154 , 155 , 156 ]. The term “super foods” includes products that are used as foods and medicine, which are edible [ 153 ].…”

Section: Resultsmentioning

confidence: 99%

Comparison between the Biological Active Compounds in Plants with Adaptogenic Properties (Rhaponticum carthamoides, Lepidium meyenii, Eleutherococcus senticosus and Panax ginseng)

Todorova

Ivanov

Ivanova

2021

Plants

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Background: In the 1960s, research into plant adaptogens began. Plants with adaptogenic properties have rich phytochemical compositions and have been used by humanity since ancient times. However, it is not still clear whether the adaptogenic properties are because of specific compounds or because of the whole plant extracts. The aim of this review is to compare the bioactive compounds in the different parts of these plants. Methods: The search strategy was based on studies related to the isolation of bioactive compounds from Rhaponticum carthamoides, Lepidium meyenii, Eleutherococcus senticosus, and Panax ginseng. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed. Results: This review includes data from 259 articles. The phytochemicals isolated from Rhaponticum carthamoides, Lepidium meyenii, Eleutherococcus senticosus, and Panax ginseng were described and classified in several categories. Conclusions: Plant species have always played an important role in drug discovery because their effectiveness is based on the hundreds of years of experience with folk medicine in different nations. In our view, there is great potential in the near future for some of the phytochemicals found in these plants species to become pharmaceutical agents.

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“…Previous study reported that, total saponin content in Mandshurica aralia was 9.41 to 10.4 percent (39). In wild Paris polyphylla, the total saponins content content in the rhizome is 2.021 and in the root the content is 0.263% (40). Similar finding were reported for methanol extract of maca leaves, total saponin content recorded was 6.09 mg / 100 g and in maca roots was 5.10 mg / 100 g (41).…”

Section: Total Saponin Content (Tsc) Determinationmentioning

confidence: 90%

Antioxidative properties of isolated saponins of Verbesina encelioides (Cav.) Benth. & Hook. fil ex Gray and SEM studies of synthesized green nanoparticles for acne management

Verma

Chaudhary

2019

Plant Sci. Today

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Acne is one of the most common and chronic skin problems in most adolescents and young adults due to several internal and external factors. The present study emphasizes on screening of high antioxidant potential of wild sunflower for acne therapy, as it also plays a major role in the patho-physiology of acne. The anti-oxidant potential of extracted plant compounds was carried out by using 1, 1-diphenyl-2-picryl hydrazyl (DPPH) and ferric reducing antioxidant power (FRAP). In recent years, scientists have been involved in the application of green nanoparticle synthesis. Further synthesized green nanoparticles were checked for antiacne potential. Isolated saponins and their synthesized nonolparticles would play an important role to control the acne.

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Physicochemical and antioxidant properties of methanol extract from Maca (Lepidium meyenii Walp.) leaves and roots

Cited by 18 publications

References 51 publications

Evaluation of Phytochemical, Antimicrobial and Antioxidant Capacities of Pennisetum purpureum (Schumach) Extracts

Evaluation of Phytochemical, Antimicrobial and Antioxidant Capacities of Pennisetum purpureum (Schumach) Extracts

Comparison between the Biological Active Compounds in Plants with Adaptogenic Properties (Rhaponticum carthamoides, Lepidium meyenii, Eleutherococcus senticosus and Panax ginseng)

Antioxidative properties of isolated saponins of Verbesina encelioides (Cav.) Benth. & Hook. fil ex Gray and SEM studies of synthesized green nanoparticles for acne management

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