Exposure assessment of selected pesticide residues using occurrence data in foods and serum samples in Pakistan

Abstract

Pesticides have emerged as a global threat to human health, especially in developing countries. In this study, we examined nine major types of pesticide residues in the food commodities (8 groups) and serum samples (n = 80) of people living in the region of Southern-Punjab, Pakistan. Pesticide residues quantification was performed using gas chromatograph coupled with electron capture detector (GC-ECD). The estimated daily intakes of the selected pesticide residues through consumption of food were also calculated. The concentration of analyzed pesticide residues in food was found below the EU maximum permissible limits except for α-HCH, and β-HCH. The highest risk of cancer was found to be associated with the consumption of HCHs contaminated cereals than other products. The incidence rate of pesticide residues in the serum samples of studied subjects was 96.25%. Pearson correlation test showed no significant correlation between thyroid hormone levels of the studied population group and the analyzed pesticide residues in the food commodities (p>0.05). Findings of this study indicate that people of Southern-Punjab, Pakistan are exposed to pesticides via food chain although non-significant health implications were recorded, the levels of a few pesticides need to be curtailed.

Determination of pyraclostrobin residue in wax gourd and its dietary risk assessment

“…It has the characteristics of broad spectrum and high efficiency and been used in more than 150 crops in more than 60 countries around the world. According to the pesticide rugged, and safe) is a sample pretreatment technology based on dispersive solid phase extraction, and it has been widely used in recent years (Fazal et al, 2022;Wang et al, 2022). This research develops a modified QuEChERS method coupled with HPLC-MS/MS and determine the residual pyraclostrobin in wax gourd.…”

The research of effect of diluents to the amount of pesticide residues in wine

“…The density of pesticides and the maximum residue limitation, the collecting of pesticide residue in human bload, the assessment of the pesticide effect, the contuct between pesticides and food poisoning, the use of biopesticides are brought to agenda on food product during conducted research (Fazal et al, 2022;Lopes & Nascimento, 2021). The serious cardiovascular diseases risks are observated having increase the concentration of toxic pollutants (Khwaja et al, 2023).…”