Effect of molecular weight on hypolipidemic and hypoglycemic activities of fermented Auriculaia auricula supernatant

Bao, Yihong; Sun, Kun; Guo, Yiting

doi:10.1590/fst.00519

Cited by 4 publications

(1 citation statement)

References 32 publications

(30 reference statements)

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“…α-Amylase and α-glucosidase are enzymes that promote the breaking of α-1,4-glycosidic bonds in starch, maltose, sucrose and oligosaccharides and hydrolyze them into monosaccharide that are easy to digest and be absorbed by the human body, such as glucose [ 106 ]. This caused the postprandial blood glucose levels of diabetic patients to increase and insulin sensitivity to be reduced, even lead them to serious complications and aggravate the condition [ 110 ]. Chen et al found that IOPS could reduce the absorption of carbohydrates by inhibiting the activity of intestinal α-amylase and α-glucose, effectively reducing postprandial blood glucose levels, repairing islet damage, and improving complications [ 111 ].…”

Section: Biological Activitymentioning

confidence: 99%

Recent Developments in Inonotus obliquus (Chaga mushroom) Polysaccharides: Isolation, Structural Characteristics, Biological Activities and Application

Jia

Xue

et al. 2021

Polymers

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Inonotus obliquus (Chaga mushroom) is a kind of medicine and health food widely used by folk in China, Russia, Korea, and some occidental countries. Among the extracts from Inonotus obliquus, Inonotus obliquus polysaccharide (IOPS) is supposed to be one of the major bioactive components in Inonotus obliquus, which possesses antitumor, antioxidant, anti-virus, hypoglycemic, and hypolipidemic activities. In this review, the current advancements on extraction, purification, structural characteristics, and biological activities of IOPS were summarized. This review can provide significant insight into the IOPS bioactivities as their in vitro and in vivo data were summarized, and some possible mechanisms were listed. Furthermore, applications of IOPS were reviewed and discussed; IOPS might be a potential candidate for the treatment of cancers and type 2 diabetes. Besides, new perspectives for the future work of IOPS were also proposed.

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Section: Biological Activitymentioning

confidence: 99%