BackgroundAirflow limitation frequently leads to the interruption of activities of daily
living (ADL) in patients with Chronic Obstructive Pulmonary Disease (COPD). These
patients commonly show absence of ventilatory reserve, reduced inspiratory reserve
volume, and dynamic hyperinflation (DH).ObjectiveTo investigate ventilatory response and DH induced by three ADL-based protocols in
COPD patients and compare them to healthy subjects.MethodCross-sectional study. COPD group: 23 patients (65±6 years, FEV1
37.2±15.4%pred); control group: 14 healthy subjects (64±4 years) matched for age,
sex, and body mass index. Both groups performed all three tests: Glittre-ADL test;
an activity test that involved moving objects on a shelf (TSHELF); and
a modified shelf protocol isolating activity with upper limbs
(TSHELF-M). Ventilatory response and inspiratory capacity were
evaluated.ResultsBaseline ventilatory variables were similar between groups (p>0.05). The
ventilatory demand increased and the inspiratory capacity decreased significantly
at the end of the tests in the COPD group. Ventilatory demand and DH were higher
(p<0.05) in the TSHELF than in the TSHELF–M in the COPD
group (p<0.05). There were no differences in DH between the three tests in the
control group (p>0.05) and ventilatory demand increased at the end of the tests
(p<0.05) but to a lower extent than the COPD group.ConclusionThe TSHELF induces similar ventilatory responses to the Glittre-ADL
test in COPD patients with higher ventilatory demand and DH. In contrast, the
ventilatory response was attenuated in the TSHELF-M, suggesting that
squatting and bending down during the Glittre-ADL test could trigger significant
ventilatory overload.