Protective function of albiflorin against ferroptosis in exhaustive exerciseinduced myocardial injury via the AKT/Nrf2/HO-1 signaling
Zhuang Tian,
Zhenyu Li
Abstract:Purpose:
It has been reported that exhaustive exercise (EE) causes myocyte injury, and eventually damages the function of the myocardia. Albiflorin (AF) has anti-inflammatory, antioxidant, and anti-apoptosis effects. In this study, we determined whether AF could mitigate the EE-induced myocardial injury and research the potential mechanisms.
Methods:
The rat model of EE was built by forced treadmill running method. Rats were intraperitoneally injected with AF before EE … Show more
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