Serum uric acid and leg ulcers

Nery, Rodrigo Araldi; Skare, Thelma Larocca

doi:10.1590/abd1806-4841.20198140

Cited by 1 publication

(1 citation statement)

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“…[96] Elevated UA levels (>500 µm) indicate wound severity with excessive ROS and inflammation, while decreased UA suggests bacterial colonization as a result of microbial uricase expression. [96,97] Currently, UAs can be detected via nonenzymatic and enzymatic approaches. [98] Sharp and colleagues reported an anodized carbon fiber mesh to detect urate by square wave voltammograms.…”

Section: Uric Acid Sensorsmentioning

confidence: 99%

Wearable Bioelectronics for Chronic Wound Management

Wang

Sani

Gao

2021

Adv Funct Materials

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Chronic wounds are a major healthcare issue and can adversely affect the lives of millions of patients around the world. The current wound management strategies have limited clinical efficacy due to labor-intensive lab analysis requirements, need for clinicians' experiences, long-term and frequent interventions, limiting therapeutic efficiency and applicability. The growing field of flexible bioelectronics enables a great potential for personalized wound care owing to its advantages such as wearability, low-cost, and rapid and simple application. Herein, recent advances in the development of wearable bioelectronics for monitoring and management of chronic wounds are comprehensively reviewed. First, the design principles and the key features of bioelectronics that can adapt to the unique wound milieu features are introduced. Next, the current state of wound biosensors and on-demand therapeutic systems are summarized and highlighted. Furthermore, the design criteria of the integrated closed loop devices are discussed. Finally, the future perspectives and challenges in wearable bioelectronics for wound care are discussed.

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