Onychocytic matricoma

D'Almeida, Luiza Ferreira; Jeunon, Thiago; Leverone, Andréia Pizarro; Nakamura, Robertha

doi:10.1590/abd1806-4841.20197865

Cited by 6 publications

(10 citation statements)

References 9 publications

(15 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We suggest that the dermoscopic finding of milia‐like cysts may be useful for the diagnosis of ungual SK, although clinically and pathologically it is often difficult to differentiate between ungual SK and OCM. Some dermoscopic findings of OCM were similar to those of ungual SK, such as longitudinal streaks with various colors (white, yellow, tan, and dark brown), splinter hemorrhages, 12 and localized thickening of the nail plate with subungual hyperkeratosis at the hyponychium 13 . On the contrary, the tip of OCM shows a honeycomb‐like cavity with thickening and deformation of the nail plate, which is more pronounced in the late stages 14 .…”

Section: Discussionmentioning

confidence: 80%

“…Some dermoscopic findings of OCM were similar to those of ungual SK, such as longitudinal streaks with various colors (white, yellow, tan, and dark brown), splinter hemorrhages, 12 and localized thickening of the nail plate with subungual hyperkeratosis at the hyponychium. 13 On the contrary, the tip of OCM shows a honeycomb-like cavity with thickening and deformation of the nail plate, which is more pronounced in the late stages. 14 Therefore, late lesions of OCM are likely to be differentiated by observation of the nail apex.…”

Section: Discussionmentioning

confidence: 97%

See 1 more Smart Citation

Ungual seborrheic keratosis with longitudinal melanonychia: A case report

Kameda

Togawa

Maru

et al. 2022

The Journal of Dermatology

View full text Add to dashboard Cite

In this paper, we report the case of a 71‐year‐old man with an 8‐year history of melanonychia on the right little finger, who referred to our hospital because the color of pigmented area had gradually darkened and the width had expanded. Physical examination revealed longitudinal melanonychia with brown color (4 mm in width). Dermoscopic examination revealed multiple white round clods and splinter hemorrhages. No micro‐Hutchinson sign was observed. We performed a punch biopsy (diameter 3 mm) of the nail matrix for diagnosis. Histopathological examination revealed irregular acanthosis of epithelium of the nail bed and distal matrix, which consisted of basaloid cells without nuclear atypia. Several zones exhibited cell whorls reminiscent of squamous eddies. The whorls were composed of large pink cells arranged in an onion peel‐like fashion. The basaloid cells tested negative for human papillomavirus in situ hybridization and p16 staining. The morphology of white round clods (milia‐like cysts in metaphoric term) observed in dermoscopic analysis corresponded to squamous eddies in histopathology. Considering these features, ungual seborrheic keratosis (SK) with longitudinal melanonychia was diagnosed, which is an atypical site for SK. We suggest that the dermoscopic finding of milia‐like cysts may be useful for the diagnosis of ungual SK.

show abstract

Section: Discussionmentioning

confidence: 80%

Section: Discussionmentioning

confidence: 97%

Ungual seborrheic keratosis with longitudinal melanonychia: A case report

Kameda

Togawa

Maru

et al. 2022

The Journal of Dermatology

View full text Add to dashboard Cite

show abstract

“…The median age of presentation is the fifth decade of life, but a case in a 12-year-old patient has been reported. 3,6 Diagnosis of OCM is challenging. OCM presents with nail-plate abnormalities, including a pigmented, thickened and rough surface associated with increased transverse curvature (pachymelanonychia).…”

Section: Discussionmentioning

confidence: 99%

“…In contrast to onychocytic carcinoma, OCM does not display cellular atypia, nuclear pleomorphism, prominent nucleoli or mitotic figures. 5,6 OCM differs from onychopapilloma that is a tumour of the distal matrix affecting the entire nail unit and showing epithelial hyperplasia, deep clefts and nail bed papillomatosis, whereas onychomatricoma is a fibroepithelial tumour and shows nail-bed papillomatosis with a cellular stroma and collagen fibres.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Nail‐plate dystrophy of the fifth toenail: thinking outside the box

et al. 2020

View full text Add to dashboard Cite

A 59-year-old white woman presented with a 2-year history of a moderately painful nail-plate abnormality of the fifth toenail (Fig. 1a). Her medical history included a cutaneous melanoma. Onychoscopy showed longitudinal thickening of the nail plate, with an irregular/rough surface, an increased transverse curvature and a yellowish colour. Splinter haemorrhages and a bluish/black blotch were detected (Fig. 1b).

show abstract

Onychocytic Matricoma: A Clinical, Dermoscopic, and Pathological Analysis of 14 Cases

Perrin,

Coutts,

Boukari

et al. 2024

The American Journal of Dermatopathology

View full text Add to dashboard Cite

Onychocytic matricoma (OCM) is a benign neoplasm of the nail matrix. Only 18 cases of this tumor have been reported in the literature to date. We retrospectively analyzed the clinical features of 14 patients with OCM. The most common clinical feature was longitudinal xanthopachyonychia (n = 9), followed by longitudinal leukopachyonychia (=3) and longitudinal pachymelanonychia (n = 2). The most common clinical findings identified following dermoscopy and analysis at high magnification of classical photographs were free-edge thickening of the nail plate without pitting (n = 14), longitudinal ridging (n = 7), round white clods (n = 7), white dots (n = 7), and filiform hemorrhages (n = 7), followed by oval and linear white clods (n = 5), fuzzy lateral border (n = 5), and red–purple blood clods (n = 3). Nail clipping histopathology showed a thickened nail plate with multiple, small, round-to-oval spaces. The tumor expressed immunopositivity for LEF-1. Dermoscopy of the nail plate and nail clipping histology provides useful information with regards to the differential diagnosis with subungual squamous cell carcinoma and nail melanoma. Ex vivo–in vivo correlation facilitates a better dermoscopic assessment of this unique underrecognized disease. However, the differential diagnosis between OCM and onychocytic carcinoma requires biopsy of the tumor. LEF-1 as an onychogenic marker can be used to resolve the differential diagnosis between OCM and subungual longitudinal acanthoma/seborrheic keratosis.

show abstract

Onychocytic matricoma

Cited by 6 publications

References 9 publications

Ungual seborrheic keratosis with longitudinal melanonychia: A case report

Ungual seborrheic keratosis with longitudinal melanonychia: A case report

Nail‐plate dystrophy of the fifth toenail: thinking outside the box

Onychocytic Matricoma: A Clinical, Dermoscopic, and Pathological Analysis of 14 Cases

Contact Info

Product

Resources

About