Dermoscopic findings of pseudoxanthomatous mastocytosis localized on vulva

Li, Qiaofei; Zeng, Kang; Peng, Xiaoming; Wang, Fang

doi:10.1590/abd1806-4841.20188039

Cited by 4 publications

(3 citation statements)

References 5 publications

(17 reference statements)

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“…Sporadic reports describe the dermoscopy features of other genital disorders in both sexes, such as clear cell acanthoma, 121 eruptive vellus hair cysts, 122 lichen aureus, 123 median raphe cyst, 124 metastasis, 29 Mondor’s disease, 125 neutrophilic sebaceous adenitis, 126 Paget’s disease, 127 porokeratosis ptychotropica, 128 postinflammatory pigmentation, 16,17 pseudoxanthomatous mastocytosis, 129 purpura, 16 tick bite, 130,131 and verruciform xanthoma 132–134 …”

Section: Resultsmentioning

confidence: 99%

Dermoscopy of genital diseases: a review

Lacarrubba

Borghi

Verzì

et al. 2020

Acad Dermatol Venereol

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The male and female external genital regions are anatomical areas in which various types of skin disorders may occur. Although most of these conditions can be diagnosed by means of clinical examination and an accurate medical history, in most cases further investigations with time-consuming and/or invasive procedures are needed in order to reach the correct diagnosis. Dermoscopy, as a modern non-invasive tool, is able to better diagnose pigmented and non-pigmented skin tumours along with various inflammatory and infectious skin and appendage disorders. The aim of this paper was to provide a review of the use of dermoscopy in genital disorders based on published data and to include personal experience gained from real life, focusing on any possible gender difference and whether disease mucosal/ semimucosal dermoscopy features may differ from those observed on the skin. In conclusion, genital dermoscopy should always be considered during clinical inspection in order to enhance the diagnosis or to rule out those conditions that may look similar but that show a different dermoscopy pattern, thus narrowing down the differential diagnoses and avoiding unnecessary invasive investigations.

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Section: Resultsmentioning

confidence: 99%

Dermoscopy of genital diseases: a review

Lacarrubba

Borghi

Verzì

et al. 2020

Acad Dermatol Venereol

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“…Finally, an instance of pseudoxanthomatous localised mastocytosis involving the vulva showed pigmented streaks with radial distribution surrounding hair follicles, and this pattern was considered pathognomonic by the authors [ 6 ].…”

Section: Resultsmentioning

confidence: 99%

“…According to the current World Health Organization (WHO) classification, CM is divided into three forms: maculopapular cutaneous mastocytosis (MPCM) (including clinical subtypes previously known as urticaria pigmentosa [UP] and telangiectasia macularis eruptiva perstans [TMEP]), diffuse cutaneous mastocytosis (DCM), and mastocytoma of the skin [ 5 ]. Other clinical variants of CM have been described, e.g., nodular mastocytosis, plaque-type mastocytosis, pseudoangiomatous xanthelasmoid mastocytosis, and pseudoxanthomatous localised mastocytosis, though they are no longer recognised as separate entities but as clinical subtypes of either MPCM or mastocytoma based on the number of the lesions (>5 MPCM and ≤5 mastocytoma) [ 2 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 ]. The diagnosis of cutaneous mastocytosis is generally based on clinical assessment (presentation of cutaneous lesions, positive Darier’s sign, and symptoms arising from mediator release) in association with additional investigations, such as histopathological, immunohistochemical, and sometimes genetic assessment.…”

Section: Introductionmentioning

confidence: 99%

Dermoscopic Features of Different Forms of Cutaneous Mastocytosis: A Systematic Review

Sławińska

Kaszuba

Lange

et al. 2022

JCM

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The term mastocytosis refers to a heterogeneous group of disorders characterised by accumulation of clonal mast cells in different organs, most commonly in the skin. Little is known about the role of dermoscopy in the diagnostics of mastocytosis. To date, no systematic review on the dermoscopic features of cutaneous mastocytosis has been performed. The aim of this study was to summarise the current knowledge in the field as well as to identify the knowledge gaps to show possible directions for further studies, based on a systematic search of PubMed, Scopus, and Web of Science databases and related references published before 3 January 2022. Dermoscopic features, type of dermoscope, polarisation mode, magnification, and number of cases were analysed. In total, 16 articles were included in this review (3 case series and 13 case reports), analysing 148 patients with different variants of cutaneous mastocytosis; all of the studies analysed had a low level of evidence (V). The main dermoscopic features of urticaria pigmentosa included brown structureless areas, brown lines arranged in a network, and linear vessels distributed in a reticular pattern, with this last finding also being typical of telangiectasia macularis eruptiva perstans. The presence of either circumscribed yellow structureless areas or diffuse yellowish background was a constant pattern of mastocytoma, while nodular, pseudoangiomatous xanthelasmoid, and plaque-type mastocytosis were typified by light-brown structureless areas and/or pigment network, though the first two variants also showed yellow/yellow-orange structureless areas. Finally, pigmented streaks of radial distribution surrounding hair follicles were described to be a pathognomonic dermoscopic feature of pseudoxanthomatous mastocytosis. Although this review shows that the various clinical forms of cutaneous mastocytosis may feature diagnostic dermoscopic clues, it also underlines the need for further investigation as several relevant data are missing, including evaluation of dermoscopic pattern according to anatomical locations or “lesion age”, studies on rare mastocytosis variants, evaluation of the prognostic role of dermoscopy in the context of systemic involvement, and comparative analyses with common clinical mimickers.

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Reflectance confocal microscopy as a diagnostic tool for mastocytoma in children

Al-Muriesh

Abdul‐fattah

et al. 2020

Journal of the American Academy of Dermatology

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Dermoscopic findings of pseudoxanthomatous mastocytosis localized on vulva

Cited by 4 publications

References 5 publications

Dermoscopy of genital diseases: a review

Dermoscopy of genital diseases: a review

Dermoscopic Features of Different Forms of Cutaneous Mastocytosis: A Systematic Review

Reflectance confocal microscopy as a diagnostic tool for mastocytoma in children

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