2018
DOI: 10.1590/abd1806-4841.20187610
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Cutaneous metastasis of colorectal cancer

Abstract: Cutaneous metastases from internal malignant neoplasms are a rare event and a late clinical finding that is associated with disseminated disease and a poor prognosis. Skin metastases from colon tumors occur in only 4% of cases of metastatic colorectal cancer. They are most often located on the abdominal skin. We report a case of 54-year-old male patient with a cutaneous metastatic focus on the lower abdomen as the initial presenting symptom of an underlying colon cancer.

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Cited by 16 publications
(20 citation statements)
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“…Unlike skin metastases occurring in 24% of metastatic breast carcinomas, data suggests that cutaneous metastases occur in just 4% (2.3-6%) of colorectal carcinomas. They are mostly found on the skin of the abdominal wall, especially at the sites of surgical scars related to treatment of the primary tumour, as occurred in this case [6].…”
Section: Discussionmentioning
confidence: 65%
“…Unlike skin metastases occurring in 24% of metastatic breast carcinomas, data suggests that cutaneous metastases occur in just 4% (2.3-6%) of colorectal carcinomas. They are mostly found on the skin of the abdominal wall, especially at the sites of surgical scars related to treatment of the primary tumour, as occurred in this case [6].…”
Section: Discussionmentioning
confidence: 65%
“…The clinical appearance of cutaneous metastasis can assume various morphologies. It usually presents as painless, red/flesh-coloured mobile nodules, single or multiple, but they can mimic other cutaneous processes like lipomas, epidermal cyst, polyps, ulcers, cellulitis, zona zoster [ 1 - 2 , 7 - 8 ]. The ultimate diagnosis of cutaneous metastasis from CRC relies on histological evaluation.…”
Section: Discussionmentioning
confidence: 99%
“…The ultimate diagnosis of cutaneous metastasis from CRC relies on histological evaluation. CK20, CDX2 and CK7 immunostaining are the most helpful markers to distinguish common malignancies, and CRC typically expresses CK20 and CDX2 but not CK7 [ 7 - 8 , 10 ].…”
Section: Discussionmentioning
confidence: 99%
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“…Moreover, it should be differentiated from primary carcinoma of skin. Colorectal adenocarcinomas usually spread their metastases to the liver, peritoneum, pelvis, lung, and bone within the first 2 years after resection of the primary tumor [ 4 ]. Although skin metastasis of adenocarcinoma of the rectum is more rare, the most common site of skin metastasis is the middle or lower dermis of the abdomen and the perianal skin.…”
Section: Discussionmentioning
confidence: 99%