Topical corticosteroid therapy: a treatment option for nevus lipomatosus cutaneous superficialis?

Castagna, Rafaella Daboit; Benvegnú, Ana Maria; Dallazem, Lia Natália Diehl; Brutti, Catiussa Spode

doi:10.1590/abd1806-4841.20186986

Cited by 5 publications

(5 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The predilection regions of the classic form include the upper part of the thighs, lumbar and pelvic area. 3 The lesions in the presented patient were classic variants of NLCS, although this patient was not in the predilection age group. The solitary form usually manifests in isolated papules, mainly affecting adults between thirty and fifty.…”

Section: Discussionmentioning

confidence: 70%

See 1 more Smart Citation

Giant Nevus Lipomatosus Cutaneous Superficialis with Cerebriform Surfaces on the Back and Sacral Region: A Case Report

Li¹,

Xiao²,

Wang³

et al. 2022

CCID

View full text Add to dashboard Cite

Nevus lipomatosus cutaneous superficialis (NLCS) is a rare hamartoma of adipose tissue characterized by the ectopic build-up of adipose tissue among collagen bundles and proliferation of ectopic adipocytes in the dermis, which leads to an absence of connection to the subcutaneous tissue. Giant NLCS (over 15 × 15 cm) is even rarer. So far, the largest NLCS mass in the literature was a giant lesion measuring 50 × 50 cm on the sacral area reported in 2014. Herein, we report a case of an even larger NLCS lesion with a size of 106 × 30 cm on the back and sacral regions. These lesions had been left untreated and had grown from small yellowish papules and nodules to giant multilocular pedunculated masses with cerebriform surfaces over 24 years. To the best of our knowledge, the NLCS lesion presented here is the largest reported. The report aimed to increase clinicians’ awareness of this rare and easily misdiagnosed disease. Furthermore, physicians should be mindful that early recognition and appropriate treatment are essential for NLCS patients, and lesions of NLCS can coalesce into unimaginable huge masses if left untreated resulting in more significant therapeutic challenges.

show abstract

Section: Discussionmentioning

confidence: 70%

“… 14 Conservative therapeutic interventions include CO 2 ablative laser, sodium deoxycholate, phosphatidylcholine, and cryotherapy for NLCS patients in whom surgical treatment cannot achieve satisfactory results. 3 , 15 …”

Section: Discussionmentioning

confidence: 99%

Giant Nevus Lipomatosus Cutaneous Superficialis with Cerebriform Surfaces on the Back and Sacral Region: A Case Report

Li¹,

Xiao²,

Wang³

et al. 2022

CCID

View full text Add to dashboard Cite

show abstract

“…Surgical resection is curative, and no recurrence has been reported. Other treatment modalities have been attempted: CO 2 laser treatment, 14 15 cryotherapy, 16 intralesional phosphatidylcholine injection, 17 topical corticosteroid application, 18 and electrodessication. 19 However, because the lesion is large, reconstructing the defect after lesion removal is difficult.…”

Section: Discussionmentioning

confidence: 99%

The Nevus Lipomatosus Superficialis of Face: A Case Report and Literature Review

Yang,

Park

2023

Arch Plast Surg

View full text Add to dashboard Cite

Nevus lipomatosus superficialis (NLS) is a hamartoma of adipose tissue, rarely reported in the past 100 years. We treated one case, and we conducted a systematic review of the literature. A 41-year-old man presented with a cutaneous multinodular lesion in the posterior region near the right auricle. The lesion was excised and examined histopathologically. To review the literature, we searched PubMed with the keyword “NLS.” The search was limited to articles written in English and whose full text was available. We analyzed the following data: year of report, nation of corresponding author, sex of patient, age at onset, duration of disease, location of lesion, type of lesion, associated symptoms, pathological findings, and treatment. Of 158 relevant articles in PubMed, 112 fulfilled our inclusion criteria; these referred to a total of 149 cases (cases with insufficient clinical information were excluded). In rare cases, the diagnosis of NLS was confirmed when the lesion coexisted with sebaceous trichofolliculoma and Demodex infestation. Clinical awareness of NLS has increased recently. NLS is an indolent and asymptomatic benign neoplasm that may exhibit malignant behavior in terms of huge lesion size and specific anatomical location. Early detection and curative treatment should be promoted.

show abstract

“…There are two primary forms of NLS: the classical/multiple form and the solitary form. The lesions of the classical form are either congenital or fully form by the second or third decade of life [6], thought it has been reported to arise in the fifth decade as well [7]. Classical NLS is described as skin-colored papules that coalesce into plaques with cluster-like or linear distribution.…”

Section: Discussionmentioning

confidence: 99%

“…Surgical excision, as in our patient, is the mainstay of treatment, as recurrence rate are low. Cryotherapy, ultrapulse CO2 laser ablation [21], topical fludroxycortide corticosteroids [7], and intralesional injections of phosphatidylcholine and sodium deoxycholate. Kim HS [22] have been reported as non-surgical options with positive clinical response.…”

Section: Discussionmentioning

confidence: 99%

Untitled

2018

SCSOAJ

View full text Add to dashboard Cite

Nevus lipomatosis superficialis is a rare skin lesion characterized by the ectopic dermal deposition of adipose tissue. While benign, it typically presents in the second to third decade of life as regional discomfort. We present the case of multiple lesions requiring serial surgical management. Presentation of Case:The patient was a 22-year-old male who presented with multiple, soft, warty lesions histologically consistent with nevus lipomatosis superficialis. He underwent excision of the largest mass and is undergoing multiple excisions for adjacent masses.Discussion: Nevus lipomatosis superficialis is a rare connective tissue hamartoma of unclear etiology and multiple clinical subtypes. While management is typically surgical, efficacy of treatment options for multiple nearby lesions is not well characterized. Conclusion:We review the literature for nevus lipomatosis superficialis and describe a case with multiple lesions of varying chronicity. Treatment must be chosen to optimize wound healing and cosmetic outcomes.

show abstract

Topical corticosteroid therapy: a treatment option for nevus lipomatosus cutaneous superficialis?

Cited by 5 publications

References 5 publications

Giant Nevus Lipomatosus Cutaneous Superficialis with Cerebriform Surfaces on the Back and Sacral Region: A Case Report

Giant Nevus Lipomatosus Cutaneous Superficialis with Cerebriform Surfaces on the Back and Sacral Region: A Case Report

The Nevus Lipomatosus Superficialis of Face: A Case Report and Literature Review

Untitled

Contact Info

Product

Resources

About