Dermoscopic features of clear cell acanthoma

Cunha, Daniela; Kassuga-Roisman, Luiza Erthal de Britto Pereira; Silveira, Luisa Kelmer Côrtes de Barros; Macedo, Fabiane Carvalho de

doi:10.1590/abd1806-4841.20186977

Cited by 13 publications

(8 citation statements)

References 7 publications

(7 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In case 2, a thicker epidermis and more prominent vascular findings were observed than in case 1. However, there was lower inflammatory cell infiltration around the tumor in case 2 than in case 1, and this was in agreement with the results of few similar case reports on CCA, with a clinical course of approximately 10 years from onset showing the same histopathological features 5,14 . Consequently, unlike irritated SK, which exacerbates with inflammation within a short period of time, CCA often grows gradually with some inflammatory involvement.…”

Section: Discussionsupporting

confidence: 90%

Differences in dermoscopic findings between early and mature clear cell acanthoma

Iseki

Negishi

Nakano

et al. 2020

The Journal of Dermatology

View full text Add to dashboard Cite

Clear cell acanthoma (CCA) is a rare benign epidermal tumor that is difficult to diagnose by visual inspection. Conversely, its diagnosis by dermoscopy is relatively easy owing to the characteristic serpiginous arrangement of coiled vessels, sometimes described as the "string-of-pearls" formation. However, in few published reports, the dermoscopic diagnosis of mature CCA has been reported. Here, we report the histopathological and detailed dermoscopic findings of two CCA cases. Between these, one case was of early (~6 months) CCA exhibiting the characteristic vascular string-of-pearls formation, whereas the other was of a more mature (~10 years) CCA; although the latter case showed combined thick and thin white intersecting lines with large coiled vessels and/or red clods, it had the string-of-pearls formation. Thus, regardless of CCA maturity, the string-of-pearls formation was present. We propose that the combination of combined thick and thin white intersecting lines along with the vascular string-of-pearls formation reflecting large coiled vessels and/or red clods on dermoscopy is a diagnostic clue to mature CCA.

show abstract

Section: Discussionsupporting

confidence: 90%

Differences in dermoscopic findings between early and mature clear cell acanthoma

Iseki

Negishi

Nakano

et al. 2020

The Journal of Dermatology

View full text Add to dashboard Cite

show abstract

“…The characteristic dermoscopic findings of CCA include red dots, globules, and glomeruloid vessels arranged in a linear or serpiginous manner. In fully developed lesions, these vessels coalesce to form a symmetrical reticular pattern resembling a ‘pearl necklace’ 2 or a ‘string of pearls’ 3 . The “string of pearls” appearance differs from the appearance of psoriasis wherein vessels are homogeneously and regularly distributed and are not in a line 4 .…”

Section: Discussionmentioning

confidence: 99%

Non-Invasive Diagnosis of a Facial Tumor Using Dermoscopy and Successful Treatment with 595 nm Pulsed Dye Laser

et al. 2021

View full text Add to dashboard Cite

Clear cell acanthoma (CCA) is an uncommon, benign epithelial tumor presenting as a well-defined, slow-growing solitary nodule. The diagnosis of CCA is usually based on clinical and histopathological evaluation of the tumor. However, when such type of benign tumor occurs on an exposed area, a biopsy is not always the best diagnostic option since it may leave scar. The recent advent of dermoscopy has offered an accurate and non-invasive method to diagnose CCA without resorting to skin biopsy. A 40-year-old male presented with a shiny, erythematous-to-brown, flattened nodule on the left cheek. Dermoscopic examination revealed a ‘string of pearls’ vascular pattern, a characteristic dermoscopic feature of CCA. Under the clinical and dermoscopic impression of CCA, a 595 nm pulsed dye laser (PDL) therapy targeting the vascular tissue in the superficial dermis of the lesion was chosen for a minimally invasive treatment. After repeated sessions of PDL, an optimal cosmetic outcome was achieved and no recurrence was recorded during the follow-up period. Herein, we report a case of presumed CCA which was successfully diagnosed and treated by utilizing non-invasive modalities.

show abstract

“…Bei unbekannter Inzidenz und Prävalenz ist die Häufigkeit der Klarzellakanthome (KZA) datenbasiert nicht einzuschätzen. Somit ist es auch nicht verwunderlich, dass die Häufigkeit des Tumors von einzelnen Autoren unterschiedlich als „selten“, „keineswegs allzu selten“ oder „relativ häufig“ angegeben wird 1–3]. In der Literatur finden sich neben Kasuistiken nur wenige retrospektive Untersuchungen klinischer Fälle, bei denen die Daten von 5–20 Patienten erfasst werden konnten 3–5].…”

Section: Epidemiologieunclassified

Klarzellakanthome

Wagner

Back

Sachse

2021

J Deutsche Derma Gesell

View full text Add to dashboard Cite

Zusammenfassung Das Klarzellakanthom ist ein selten diagnostizierter Tumor, der aufgrund variabler klinischer Morphologie in der Regel erst anhand seiner histopathologischen Merkmale erkannt wird. Die Primäreffloreszenz ist eine wenige Millimeter durchmessende rote Papel, die als einzelne Läsion häufig an den unteren Extremitäten auftritt. In der Dermatoskopie gilt eine Perlenkettenstruktur der Gefäße (strings of pearls) als weitgehend spezifischer Befund der Klarzellakanthome. Im Gegensatz zu dem zunächst uncharakteristischen klinischen Befund ist das histopathologische Bild der Klarzellakanthome durch eine typische kompakte, scharf begrenzte Akanthose gekennzeichnet, bestehend aus hellen, PAS‐reaktiven Keratinozyten. Bei ungeklärter Ätiologie und Pathogenese ist auch die Nosologie der Klarzellakanthome umstritten. Diskutiert wird die Einordnung als kutane Neoplasie oder als reaktive inflammatorische Dermatose.

show abstract

Dermoscopic features of clear cell acanthoma

Cited by 13 publications

References 7 publications

Differences in dermoscopic findings between early and mature clear cell acanthoma

Differences in dermoscopic findings between early and mature clear cell acanthoma

Non-Invasive Diagnosis of a Facial Tumor Using Dermoscopy and Successful Treatment with 595 nm Pulsed Dye Laser

Klarzellakanthome

Contact Info

Product

Resources

About