Subcorneal pustular dermatosis in the pediatric age

Abstract

Subcorneal pustular dermatosis is a rare pustular eruption which occurs mainly in middle-aged women and rarely during childhood. We report a case of a 15-year-old female with a 4-year history of pustular lesions on the proximal region of the upper limbs with subsequent impairment of the trunk. Physical examination revealed small pustules distributed on the trunk and proximal region of the limbs. Histopathology showed a subcorneal pustule and direct immunofluorescence for IgA, IgM, IgG and fibrinogen was negative, confirming the diagnosis of subcorneal pustular dermatosis. The patient was treated with dapsone with good clinical response after one month. Subcorneal pustular dermatosis is a rare condition and there are only isolated cases reported in the literature in pediatric patients. Thus, we discuss the main clinical aspects and treatment response of this condition during childhood.

Extensive Erythematous Pustular Plaques in an Elder Woman: Answer

“…2 It is considered a rare disease with an unknown etiopathogenesis that affects mainly adults with predominance in middle-age women, although pediatric series have been also reported. 3…”

“…2 It is considered a rare disease with an unknown etiopathogenesis that affects mainly adults with predominance in middle-age women, although pediatric series have been also reported. 3 Clinically, SPD presents abruptly with flaccid pustules or vesicles that rapidly may adopt annular morphology, with peripheral pustules and a central clearing. Although SPD pustules most characteristically arise on normal-appearing skin, pustules may also appear on the erythematous skin.…”