Histoid leprosy: a rare exuberant case

Andrade, Pedro José Secchin de; Messias, Sulamita Dos Santos Nascimento Dutra; Ferreira, Paola Cristina Brandão Oliveira; Sales, Anna Maria; Machado, Adriana Rodrigues; Nery, José Augusto da Costa

doi:10.1590/abd1806-4841.20154049

Cited by 4 publications

(2 citation statements)

References 5 publications

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“…These would not adequately present the antigens to the effector cells of the immune system, which could explain the origin of hyperplastic lesions with numerous bacilli and scarce globi formation. 5 , 6 , 7 …”

Section: Discussionmentioning

confidence: 99%

Histoid leprosy presenting as a large tumor

Fernandes

Andrade

Nascimento

et al. 2021

Anais Brasileiros de Dermatologia

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Histoid leprosy is a rare form of multibacillary leprosy, characterized by the presence of papules, plaques, or nodules whose appearance is keloid-like, skin colored, or erythematous. Fusiform cells are the main histopathological feature. Due to the fact that it can simulate other dermatological lesions, for example, dermatofibroma and neurofibroma, it constitutes a diagnostic challenge for clinicians and pathologists. It is a bacilliferous form of leprosy, and it plays an important role in disease transmission. A case of a patient with histoid leprosy living in the Northeast Region of Brazil is reported.

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Section: Discussionmentioning

confidence: 99%

Histoid leprosy presenting as a large tumor

Fernandes

Andrade

Nascimento

et al. 2021

Anais Brasileiros de Dermatologia

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“…Once microorganisms reach a high bacillary load, the host acts as a source of reservoir 9,11,12 and spreads the disease. Moreover, children with delayed diagnosis and appropriate treatment are faced with various degrees of incapacity, which compromises their future working capacity.…”

Section: Discussionmentioning

confidence: 99%

Wade’s histoid leprosy in a 14-year-old teenage boy

Figueira

Oliveira

Souza

et al. 2017

Rev. Soc. Bras. Med. Trop.

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Wade's histoid leprosy (HL) is a rare variant of multibacillary leprosy, with characteristic clinical, immunologic, histopathologic, and bacteriologic features. It is associated with resistance to sulfa drugs or polychemotherapy and is rarely observed in patients who have not undergone prior treatment. Clinically, HL resembles keloid or dermatofibroma. Furthermore, HL is rare in children and is difficult to diagnose even by experts. This report describes a case of HL in a 14-year-old Brazilian boy, who presented with multiple nodular and tumor-like lesions, simulating keloids. He had not undergone prior treatment with anti-leprosy drugs, which accentuates the relevance of this case report.

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