Lichen planopilaris epidemiology: a retrospective study of 80 cases

Abstract

BACKGROUNDLichen planopilaris is a frequent presentation of primary cicatricial alopecia. Scalp distribution characterizes the main clinical presentations: classic lichen planopilaris, frontal fibrosing alopecia and Graham-Little Piccardi-Lassueur Syndrome (GLPLS).OBJECTIVEDescription of the clinical, dermoscopic and histopathological findings of Lichen planopilaris in public and private practices.METHODA retrospective observational study was performed by reviewing medical records of patients with lichen planopilaris.RESULTSEighty patients were included, 73 (91,25%) were female. Prototype II was seen in 53 (66,25%) patients. Classic lichen planopilaris was seen in 62,5% of the cases. Frontal fibrosing alopecia was seen in 31% of the patients and only one patient presented Graham-Little Piccardi-Lassueur Syndrome (GLPLS). Scalp lesions were scattered throughout the scalp in 47 (58,75%) of the patients, while 24 (30%) presented mainly central scalp lesions, 29 (36,25%) presented marginal lesions and only 4 (5%) patents had vertex lesions.CONCLUSIONSClinical presentation of Lichen planopilaris varies. To recognize the heterogeneity of the clinical appearance in lichen planopilaris is important for differential diagnosis.

Isolated Body Hair Loss: An Unusual Presentation of Lichen Planopilaris

“…Pain, itching or burning sensations may be associated and indicate disease activity [2,4]. The possibility of body hair involvement is well established in some variants of LPP, such as FFA and LGLPS.…”

Trichoscopy of primary cicatricial alopecias: an updated review

“…In such cases, the main trichoscopic finding was groups of 2–4 hairs emerging from a single ostium surrounded by perifollicular and interfollicular scaling and erythema. Few other studies have also reported compound hairs and hair tufting in LPP …”

“…This folliculocentric inflammatory process is the reason of perifollicular clinical and trichoscopic signs in LPP. Frequently reported trichoscopic findings of LPP include the absence of follicular openings, peripilar scaling and erythema, blue‐grey dots in a target pattern and preserved pinpoint white dots …”

“…Frequently reported trichoscopic findings of LPP include the absence of follicular openings, peripilar scaling and erythema, blue-grey dots in a target pattern and preserved pinpoint white dots. 1,3,[32][33][34] Peripilar casts are concentrically arranged layers of scales which typically surround the terminal hairs present within or surrounding the alopecic patch and are better visualized using dry dermoscopy. 5 These casts represent hyperkeratosis and lamellar fibrosis resulting due to perifollicular lichenoid inflammation.…”

Clinical Description of Frontal Fibrosing Alopecia with Concomitant Lichen Planopilaris

“…Although both of these diseases are scarring alopecias, their coexistence could lead to misdiagnosing one of them. Involvement of non-scalp hair areas and presence of symptoms could be more frequent in these patients [9,10]. …”