Frontal cutaneous meningioma - Case report

Abstract

Cutaneous meningiomas are rare tumors most commonly located on the scalp. We report the case of a 55-year-old male who presented with a 2x3 cm tumoral lesion on the forehead. The lesion was hard, adherent and covered by normal skin. Incisional biopsy revelead a proliferation of monomorphic round cells, organized in nests and focally forming pseudovascular spaces. Immunohistochemical study revealed positivity for epithelial antigen membrane and vimentin. Vascular markers, cytokeratins and S100 protein were negative. A brain CT scan did not show any evidence of intracranial meningioma. The authors describe the case of a cutaneous frontal meningioma in probable relation with previous cranioencephalic trauma.

Type I cutaneous meningioma of dorsal thoracic spine (Rudimentary Meningocele): A rare entity at an unusual site

“…12 As these lesions are rare and they don't have a definite characteristic appearance, cutaneous meningiomas can be clinically confused as various cysts, epithelioid sarcomas, hidradenomas, fibromas, adnexal lesions, neuroectodermal tumors, metastatic lesions. 13,14 Thus it is imperative to subject tissue for histopathological examination and IHC should be performed wherever indicated.…”

“…Meningothelial cells in nests, sheets or lobules with collagen bodies or psammoma bodies are useful clues. 14 IHC should be performed wherever necessary. These cells are EMA and vimentin positive and negative for CK, S100, CD34, CD31, CD68, SMA and desmin thus excluding other origin of cells.…”

“…These cells are EMA and vimentin positive and negative for CK, S100, CD34, CD31, CD68, SMA and desmin thus excluding other origin of cells. 14 Midline or paramidline located similar lesions should be differentiated from dermal sinus tract, myelocele and meningomyelocele, perineuromas, lipomas, fibrohistiocytomas and fibromyxoid sarcomas. 2 Type I CM or Rudimentary meningocele (RM) is a rare developmental anomaly characterized by a mass in the posterior midline along the craniospinal axis.…”

“…1 Vascular endothelial growth factor inhibitors and Platelet-derived growth factor inhibitors are under trial for treatment of such tumors. 12,14 After intensive search, we found 8 other reported cases of cutaneous meningioma in the Indian literature, out of which 7 were located in the scalp and one in the submandibular region. 1,13,[15][16][17][18][19][20] This is the 4 t h Indian case of Rudimentary meningocele and the 1 st case of RM to be located in the spine in the Indian literature.…”

Cutaneous meningioma: A cytomorphological diagnosis

“…They are derived from arachnoid cells of meninges. Rarely, they can present extracranially,[ 1 ] where they are accessible to fine needle aspiration cytology (FNAC) and pose a diagnostic dilemma. Here, we report a case of cutaneous meningioma of parieto-occipital region to emphasize the importance of keeping it as one of the differential diagnosis in the pathological evaluation of scalp swelling.…”