Membranous lipodystrophy: case report and review of the literature

Abstract

Membranous lipodystrophy is a distinct type of membranocystic fat necrosis. It is associated with many local and systemic diseases, including vascular disorders. The histopathological changes which characterize this phenomenon are variably sized cysts in the fat lobules of the subcutaneous tissue, which are surrounded by eosinophilic membranes projecting into the cystic space. We report a case of secondary membranous lipodystrophy associated with both hypertension and venous insufficiency.

Fat and MEAT. A rare benign lesion of adipose tissue

“…Saponization, foamy histiocytes, and inflammatory infiltrates characteristic of pancreatic fat necrosis are completely missing in MEAT (6). Membranocystic fat necrosis (or membraneous lipodystrophy) is non-capsulated and has multiple cysts, and their membranes are reactive with period acid-Schiff reagent (PAS) (22). A mobile solid tumor has yet not been detected.…”