Sweet Syndrome in childhood

Santos, Talita Batalha Pires dos; Sales, Barbara Cristina Gouveia; Sigres, Marianne; Rosman, Fernando Colonna; Cerqueira, Ana Maria Mosca de

doi:10.1590/abd1806-4841.20153247

Cited by 7 publications

(5 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…1B). Our patient showed 1) sudden onset of erythematous plaques, 2) neutrophilic dermal infiltrate (2 major criteria), 3) fever, 4) rapid response to steroid therapy (2 minor criteria)1. Consequently, on basis of clinical, histologic, lab findings, and criteria, we could diagnose as SS.…”

mentioning

confidence: 73%

Fournier's Gangrene: A Rare Complication of Sweet's Syndrome

Choi

Kim

et al. 2017

Ann Dermatol

View full text Add to dashboard Cite

mentioning

confidence: 73%

Fournier's Gangrene: A Rare Complication of Sweet's Syndrome

Choi

Kim

et al. 2017

Ann Dermatol

View full text Add to dashboard Cite

“…SS in patients receiving treatment with ATRA for APL is a clinical marker of effectiveness of the drug to successfully induce promyelocyte maturation [ 18 ]. Generally, patients with SS present neutrophilia; however, if associated with a malignant hematological disease, cytopenias may occur [ 20 ]. Histologically, infiltration of the dermis by neutrophils and subdermal edema without leukocytoclastic vasculitis is observed [ 13 ].…”

Section: Discussionmentioning

confidence: 99%

Sweet Syndrome in an Adolescent Patient With Differentiation Syndrome Secondary to Promyelocytic Leukemia Treatment With All-Trans Retinoic Acid

et al. 2021

View full text Add to dashboard Cite

Sweet syndrome (SS) is an acute febrile neutrophilic dermatosis that is histologically characterized by an infiltration of the dermis by neutrophils. A 12-year-old adolescent female patient recently diagnosed with acute promyelocytic leukemia presented with fever and was hospitalized for antibiotic management after 22 days of being treated with a treatment protocol based on daunorubicin, all-trans retinoic acid (ATRA), and prophylaxis with dexamethasone, the patient developed erythematous skin lesions located mostly on the extremities. Lesions evolved into painful subcutaneous nodules, and one lesion evolved into a 2.5-cm blister with a purple and necrotic base. A skin biopsy was performed and showed neutrophilic dermatosis which confirmed the diagnosis of SS. The patient's clinical features complied with criteria for differentiation syndrome complicated by shock. Two days after ATRA was suspended, the patient presented resolution of the fever and skin lesions. SS is a rare neutrophilic dermatosis secondary to an innate immune disorder classified into four categories: classical (idiopathic), para-inflammatory, paraneoplastic or pregnancy-related. SS has been described in patients with acute myeloid leukemia in adults secondary to the use of drugs such as ATRA or as a part of a paraneoplastic syndrome. SS can occur exceptionally in children with myeloid leukemia secondary to the use of drugs such as ATRA.

show abstract

“…Das 1964 beschriebene Sweet-Syndrom, die akute neutrophile Dermatose, ist eine Erkrankung des Erwachsenenalters [ 22 ]. Nur 8 % aller Sweet-Syndrome treten im Kindesalter auf [ 19 , 25 ]. Typischerweise finden sich wie bei unserer Patientin druckdolente Papeln und Plaques zusammen mit Fieber und weiteren Allgemeinsymptomen sowie laborchemische Neutrophilie.…”

Section: Diskussion Und Review Der Literaturunclassified

Sweet-Syndrom des Kindesalters mit erworbener Cutis laxa (Marshall-Syndrom) als Erstmanifestation einer Takayasu-Arteriitis

2022

View full text Add to dashboard Cite

ZusammenfassungEine Besonderheit des seltenen Sweet-Syndroms des Kindesalters ist die fakultative Abheilung in Form einer postinflammatorischen Elastolyse mit erworbener Cutis laxa, die nach dem Erstbeschreiber als Marshall-Syndrom benannt wird. Wir berichten von einem 3‑jährigen Kind, bei dem ein derartiges Sweet-Syndrom zur Erstdiagnose einer Takayasu-Arteriitis führte. Die postinflammatorische Elastolyse mit erworbener Cutis laxa stellt beim kindlichen Sweet-Syndrom einen klinisch relevanten kutanen Indikator für lebensbedrohliche kardiale Gefäßkomplikationen wie Aortitis, Aortenaneurysma, Koronararterienstenose und Herzversagen dar. Da das Cutis-laxa-artig abheilende Sweet-Syndrom den kardialen Komplikationen zumeist zeitlich vorausgeht oder wie in unserem Fall simultan auftritt, sollten die betroffenen Patienten umgehend kardiologisch und rheumatologisch untersucht werden, um bei vaskulärer Beteiligung einen komplikativen Verlauf durch frühe antiinflammatorische und immunmodulierende Systemtherapie zu verhindern.

show abstract

Sweet Syndrome in childhood

Cited by 7 publications

References 5 publications

Fournier's Gangrene: A Rare Complication of Sweet's Syndrome

Fournier's Gangrene: A Rare Complication of Sweet's Syndrome

Sweet Syndrome in an Adolescent Patient With Differentiation Syndrome Secondary to Promyelocytic Leukemia Treatment With All-Trans Retinoic Acid

Sweet-Syndrom des Kindesalters mit erworbener Cutis laxa (Marshall-Syndrom) als Erstmanifestation einer Takayasu-Arteriitis

Contact Info

Product

Resources

About