Melanoma developed during pregnancy - A case report

Mestnik, Natalia Cammarosano; Afonso, Joao Paulo Junqueira Magalhães; Enokihara, Mílvia Maria Simões e Silva; Enokihara, Mauro Yoshiaki; Porro, Adriana María; Hirata, Sérgio Henrique

doi:10.1590/abd1806-4841.20132359

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“…[28][29][30] Two-thirds of melanomas occur in pre-existing naevi, and therefore any changing pigmented lesion should be biopsied. 4,12,13,24,[31][32][33]…”

Section: Delayed Diagnosismentioning

confidence: 99%

Melanoma in pregnancy

Still

Brennecke

2017

Obstet Med

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Melanoma is one of the most common cancers diagnosed in pregnancy and has a high metastatic potential. As the incidence of melanoma increases, careful clinical evaluation of suspicious skin lesions remains the mainstay of early diagnosis. There is controversy in the literature as to whether pregnancy-associated melanoma has worse survival than other melanomas. Any changing-pigmented lesion should be biopsied, regardless of pregnancy hyperpigmentation. Increased lymphangiogenesis in pregnancy is associated with increased metastasis - timely diagnosis is therefore imperative. While the effect of oestrogen and progesterone on melanoma is under investigation, it is generally accepted that oral contraceptive use in not contraindicated after a diagnosis of melanoma in pregnancy. Subsequent pregnancy should be delayed for two to three years after a diagnosis of melanoma with a high risk of recurrence.

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“…[28][29][30] Two-thirds of melanomas occur in pre-existing naevi, and therefore any changing pigmented lesion should be biopsied. 4,12,13,24,[31][32][33]…”

Section: Delayed Diagnosismentioning

confidence: 99%