Cutaneous metastasis from internal carcinomas: a review of 45 years

Sittart, José Alexandre de Souza; Senise, Monica

doi:10.1590/abd1806-4841.20131165

Cited by 37 publications

(47 citation statements)

References 4 publications

(5 reference statements)

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“…Most cutaneous metastases appear as mobile solitary or multiple, flesh-colored dermal or subcutaneous nodules which are variable in size and are usually painless [5,10,18] . Other presentations include telangiectatic violaceous papulovesicles, alopecia neoplastica, nonulcerative papules, erythematous-infiltrating plaques, and zosteriform metastasis [5] .…”

Section: Discussionmentioning

confidence: 99%

Cutaneous Metastasis: A Study of 138 Cases Diagnosed by Fine-Needle Aspiration Cytology

Handa¹,

Kundu²,

Dimri

2016

Acta Cytologica

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Background: Cutaneous metastases can occur in a wide variety of internal malignancies and may be the first sign of a clinically silent visceral cancer. Study Design: A retrospective analysis was made of 138 cases diagnosed with cutaneous and subcutaneous metastasis on fine-needle aspiration cytology (FNAC). Primary tumors of the skin/subcutis were excluded. Results: Of 138 cases, the primary was known in 101 cases and unknown in 37 cases. The age of the patients ranged from 5 to 86 years, and 76 (55.1%) were male and 62 (44.9%) were female. Clinically, the most common lesion was a single nodule (n = 77, 55.8%). The chest wall was the predominant site (n = 53, 38.4%). In males and females, the most common primary sites were the lung (n = 16) and breast (n = 24), respectively. On cytology, the most common diagnosis was metastatic adenocarcinoma (n = 41, 29.7%). Of 37 cases with an unknown primary, FNAC helped to locate the primary site in 17 (45.9%) cases, while in 20 cases it remained undiagnosed. Conclusions: FNAC is a rapid and safe technique that can be used as a first line of investigation for confirmation of metastatic lesions of the skin. Critical evaluation of cytomorphological features along with relevant clinical details could help in the localization of an unknown primary site in some cases.

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Section: Discussionmentioning

confidence: 99%

Cutaneous Metastasis: A Study of 138 Cases Diagnosed by Fine-Needle Aspiration Cytology

Handa¹,

Kundu²,

Dimri

2016

Acta Cytologica

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“…Another one reported a case of RCC presenting as a post-auricular lesion [6] and six years post malignant nephrectomy in the scalp area [7]. On histopathology, these cutaneous lesions follow a similar cell structure to the original tumor: clear cells that are trabecular, papillary, or both with prominent vascularity and hemosiderin deposition in the stroma [8]. Immunohistochemistry aids in the determination of the nature of the lesion, staining positive for vimentin, keratin, and epithelial membrane antigen [8].…”

Section: Discussionmentioning

confidence: 99%

A unique presentation of renal cell transformation into renal cell carcinoma in subcutaneous fatty tissue post twenty year old healing gun-shot wound: A case report

Alqahtani

2017

International Journal of Surgery Case Reports

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HighlightsAn RCC presenting as a result of malignant transformation of remnant renal cells.At a site where twenty years ago the patient had sustained a gunshot wound.He underwent several surgeries, including a nephrectomy for that gunshot trauma.The case is unique in its time course, the preceding events, & no primary lesions.Its unheard-of malignant transformation of seemingly non-functional cells.

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“…Involvement of the scalp in AN can engender through dissemination via lymphatic, hematogenous, or contiguous routes . The resultant perifollicular fibrosis and loss of follicular unit architecture seen histopathologically in AN can arise from one of two mechanisms.…”

Section: Discussionmentioning

confidence: 99%