2010
DOI: 10.1590/s2179-83972010000200009
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Incidência e preditores de revascularização da lesão-alvo no seguimento clínico de longo prazo: análise crítica do Registro DESIRE

Abstract: Reportamos a incidência e preditores de nova revascularização da lesão-alvo (RLA) numa coorte de pacientes do mundo real tratados com stents farmacológicos (SF). Método: Entre maio de 2002 e fevereiro de 2010, 3.320 pacientes de único centro foram submetidos a intervenção percutânea (ICP), eletiva ou de urgência, com implante de 5.320 SF (Cypher, 83%; Taxus, 9%; Xience V/Promus, 3%; Endeavor, 4%; BioMatrix, 1%). O seguimento clínico de até oito anos (mediana, 3,4 anos) foi completo em 98% do grupo e 129 pacien… Show more

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Cited by 3 publications
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“…[15][16][17] The observation of a poorer prognosis in diabetic patients is more consistent in the late outcome after PCI, which may be explained by higher rates of restenosis and disease progression in this group of patients. 1,[8][9][10] In Brazil, the Drug-Eluting Stent in the Real World (DESIRE registry), 18 which assessed the predictors of target lesion revascularisation in a long-term clinical follow-up, demonstrated that diabetes mellitus predisposes individuals to a greater need for new procedures. A subanalysis of the same registry, which evaluated the late outcome after PCI with drug-eluting stents in diabetic patients, showed that, when analysed in combination, major cardiac events occurred more frequently in the diabetic group, although still at very low rates.…”
Section: Discussionmentioning
confidence: 99%
“…[15][16][17] The observation of a poorer prognosis in diabetic patients is more consistent in the late outcome after PCI, which may be explained by higher rates of restenosis and disease progression in this group of patients. 1,[8][9][10] In Brazil, the Drug-Eluting Stent in the Real World (DESIRE registry), 18 which assessed the predictors of target lesion revascularisation in a long-term clinical follow-up, demonstrated that diabetes mellitus predisposes individuals to a greater need for new procedures. A subanalysis of the same registry, which evaluated the late outcome after PCI with drug-eluting stents in diabetic patients, showed that, when analysed in combination, major cardiac events occurred more frequently in the diabetic group, although still at very low rates.…”
Section: Discussionmentioning
confidence: 99%