Associação entre a densidade radiológica da placa à tomografia de coronárias com 64 colunas de detectores e a composição da placa ao ultrassom intravascular com técnica de histologia virtual: resultados de uma comparação pareada prospectiva

Abstract

Background: Little is known about the comparative results of coronary plaque assessment by multidetector computed tomography (MDCT) against the novel intravascular ultrasound virtual histology (IVUS-VH). Method: Threevessel IVUS-VH and MDCT were prospectively obtained from 21 patients. Each vessel was divided into 4-mm subsegments, which were used as the basic unit for analysis. The 4-mm subsegments were matched by their axial location. Lumen and outer vessel boundaries for IVUS-VH and for MDCT were traced by specific automatic softwares. The percent contribution of each IVUS-VH plaque tissue type and the ratio of necrotic tissue to calcium were quantified. The MDCT plaque was evaluated through its average density in Hounsfield units (HU). Results: A total of 641 matched subsegments were computed from 70 vessels. Overall, the average IVUS-VH tissue composition was: fibrous = 64%; fibrofatty = 20%; necrotic tissue = 11%; RESUMO

Avaliação ultrassonográfica intracoronária da carga aterosclerótica no tronco da artéria coronária esquerda prediz a extensão da doença no restante da árvore coronária: análise piloto

“…Nesse sentido, a angiotomografia computadorizada das artérias coronárias poderia se tornar uma ferramenta promissora. 12 Figura 3 -Imagens ilustrativas da concordância do grau de acometimento aterosclerótico nos principais ramos arteriais de um mesmo paciente. A figura mostra cortes transversais de ultrassom intravascular do tronco da artéria coronária esquerda e das três principais artérias coronárias do mesmo paciente.…”