Implante contemporâneo de stents convencionais: comparação dos stents de hastes finas de aço inoxidável versus cromo-cobalto

Abstract

Contemporary Bare Metal Stents Implantation: Comparison of Stainless Steel versus Cobalt Chromium Coronary Stents Introduction: Higher strut thickness of coronary bare metal stents is associated with restenosis risk after bare metal stent implantation. New bare metal stents with thin struts have been developed, but there have been few studies comparing these new devices. Methods: from February 2004 until January 2007, 475 consecutive patients underwent percutaneous coronary intervention treating "de novo" coronary lesions exclusively using BMS. One hundred and eleven patients with stainless steel stent (Liberté ®group I) and 364 with cobalt chromium stent (Driver ®group II). Bypass venous graft, cardiogenic shock and restenosis were excluded. Patient progress was evaluated during their hospital stay and an average 18-month outpatient follow-up. Results: Angiographic success in almost all cases, with reduced in-hospital cardiac complications. Over an average 18-month period we found a low incidence of major adverse cardiac events (10.1 vs 7.3%; p=0.2) and a reduction in target vessel revascularization procedures (8.6 vs 6.9%; p=0.3). Conclusion: Implantation of new generation BMS with thinner-struts to treat "de novo" coronary lesions, in a select population, reduces target vessel revascularization to below 10%, with both devices achieving similar results.

Evaluation of cellular response and drug delivery efficacy of nanoporous stainless steel material

“…Drug anchoring by physical methods (e.g., electrospinning, negative pressure, and lyophilization) enable the exclusion of polymers during drug-eluting stent fabrication. Of course, it has been reported that the thickness of the stent strut affects various pathological outcomes [ 27 ]. However, in this study, only the surface properties of the material were studied.…”

Influence of metal alloy and the profile of coronary stents in patients with multivessel coronary disease

“…Clinical evidence has suggested that patients treated with thin strut stents (<100 µm thick) show less neointimal proliferation and better outcomes than patients treated with stents with thicker struts. In the national registry, Salles et al (2008) 21 assessed the rate of target vessel revascularization, hospital stay and mean 18-month patient follow-up with the contemporary thin strut cobalt–chromium stents (Driver, Medtronic, United States - World Headquaters, 710 Medtronic Parkway, Minneapolis, MN 55432-5604) and stainless steel (Liberté, Boston Scientific) stents and observed no significant statistically differences between them.…”