Therapeutic success and failure in using miltefosine to treat dogs naturally infected with Leishmania infantum
Gustavo Gonçalves,
Monique Paiva de Campos,
Alessandra Silva Gonçalves
et al.
Abstract:In urban environments, domestic dogs (Canis familiaris) are a major reservoir for the parasite Leishmania infantum. Miltefosine has been used as the standard treatment for canine visceral leishmaniasis in Brazil. However, therapeutic failures have been reported. In the present study, two dogs (CG03 and CG06) with a diagnosis of infection by L. infantum underwent two cycles of treatment with miltefosine (Milteforan™ - Virbac®). Analyses showed increases in the parasite load of both CG03 and CG06, even after tre… Show more
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