Hypertension is the underlying cause of death assessed at the autopsy of individuals

Abstract

Objective: To analyze hypertension and its relationship with the causes of death identified by the autopsy. Method: Cross-sectional study analyzed 356 participants belonging to the Brazilian Aging Brain Study Group, over 50 years of age, autopsied at the Sao Paulo Autopsy Service between 2004 to 2014. A clinical interview was conducted with the informant of the deceased. Hypertension was defined by reporting the disease and/or use of antihypertensive medication, by the informant of the deceased. Descriptive analyzes and bivariate and multivariable associations were performed. Results: The prevalence of hypertension was 66.2% and it was the second leading cause of death (25.6%) identified by autopsy, preceded by atherosclerosis (37.8%). The variables associated with hypertension were: female gender (OR=2.30 (1.34-3.90)); living with partner [OR=0.55 (0.32-0.92)]; Body Mass Index [OR=1.14 (1.08-1.22)] and history of diabetes [OR=2.39 (1.34-4.27)]. Conclusion: The prevalence of hypertension was high, and it was the second most common underlying cause of death. The gold standard for the definition of cause of death, the autopsy, shows important results, which confirmed the relevance of hypertension as a public health problem.

Prevalence of systemic arterial hypertension in users from a family health unit in northern Brazil

“…Another significant variable in the present study was sedentary lifestyle, which is related to a higher prevalence of the disease in both sexes, in this case, the trend among women with a sedentary lifestyle was more likely to present SAH compared to men. Like these findings, other studies revealed that more than 50% of hypertensive individuals did not practice physical exercises, but among them, a study showed the prevalence of sedentary lifestyle among women, with a percentage of 57.5% 16 . In addition, this research showed that physical inactivity is the factor that influences survival in hypertension among men, although smoking is more prevalent, as highlighted by a study conducted in Paraná, in which the association avoided and previously dissipated with SAH 17 .…”

Cause of Death Determined by Full-body Autopsy in Neuropathologically Diagnosed Dementias

“…Samples of abnormal areas of organs such as the kidney, spleen, lung, liver, heart, and brain are collected for anatomopathologic analysis. A brief report regarding how the death occurred and preexisting diseases is also collected with a close family member to confront macro and microscopic findings 25…”

“…A brief report regarding how the death occurred and preexisting diseases is also collected with a close family member to confront macro and microscopic findings. 25 In our analysis, we have considered the CoD reported in the full-body autopsy carried out by a pathologist. As death can be a multifactorial event, all national full-body autopsy reports are filled in according to a hierarchical chain of events that led to a person's death, CoD being the last event.…”

Cardiac causes of death in Moscow and Moscow Region

“…Таким образом, вероятно, даже проведение патологоанатомических исследований в отсутствие четко прописанных согласованных на международном уровне критериев не улучшает ситуацию с определением первоначальной причины смерти. По данным исследования, выполненного в Бразилии среди 356 умерших старше 50 лет от естественных причин, артериальная гипертензия была второй ведущей первоначальной причиной смерти (25,6%) после атеросклероза (37,8%), но в статье нет критериев установления первоначальной причины смерти от артериальной гипертензии -практически у всех пациентов с этим состоянием наблюдалась коморбидная патология, и не совсем ясно, почему именно артериальная гипертензия была установлена как первоначальная причина смерти [17]. L. Rethy и соавт.…”